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- W2074017816 endingPage "214" @default.
- W2074017816 startingPage "201" @default.
- W2074017816 abstract "The organization of the genome into functional units, such as enhancers and active or repressed promoters, is associated with distinct patterns of DNA and histone modifications. The Encyclopedia of DNA Elements (ENCODE) project has advanced our understanding of the principles of genome, epigenome and chromatin organization, identifying hundreds of thousands of potential regulatory regions and transcription factor binding sites. Part of the ENCODE consortium, GENCODE, has annotated the human genome with novel transcripts including new noncoding RNAs and pseudogenes, highlighting transcriptional complexity. Many disease variants identified in genome-wide association studies are located within putative enhancer regions defined by the ENCODE project. Understanding the principles of chromatin and epigenome organization will help to identify new disease mechanisms, biomarkers and drug targets, particularly as ongoing epigenome mapping projects generate data for primary human cell types that play important roles in disease." @default.
- W2074017816 created "2016-06-24" @default.
- W2074017816 creator A5019244899 @default.
- W2074017816 creator A5071133888 @default.
- W2074017816 date "2014-03-27" @default.
- W2074017816 modified "2023-10-12" @default.
- W2074017816 title "Epigenetics, chromatin and genome organization: recent advances from the ENCODE project" @default.
- W2074017816 cites W1486257535 @default.
- W2074017816 cites W1544691147 @default.
- W2074017816 cites W1558122435 @default.
- W2074017816 cites W1921479150 @default.
- W2074017816 cites W1963958393 @default.
- W2074017816 cites W1964648031 @default.
- W2074017816 cites W1964963969 @default.
- W2074017816 cites W1965100590 @default.
- W2074017816 cites W1971382122 @default.
- W2074017816 cites W1974352732 @default.
- W2074017816 cites W1974798829 @default.
- W2074017816 cites W1977308882 @default.
- W2074017816 cites W1977632740 @default.
- W2074017816 cites W1977772936 @default.
- W2074017816 cites W1979863415 @default.
- W2074017816 cites W1984996540 @default.
- W2074017816 cites W1986365556 @default.
- W2074017816 cites W1986586739 @default.
- W2074017816 cites W1993362950 @default.
- W2074017816 cites W1993891331 @default.
- W2074017816 cites W1995915578 @default.
- W2074017816 cites W2000828917 @default.
- W2074017816 cites W2002262418 @default.
- W2074017816 cites W2005986419 @default.
- W2074017816 cites W2011463791 @default.
- W2074017816 cites W2016849135 @default.
- W2074017816 cites W2021803200 @default.
- W2074017816 cites W2022140142 @default.
- W2074017816 cites W2022587035 @default.
- W2074017816 cites W2022658418 @default.
- W2074017816 cites W2029722028 @default.
- W2074017816 cites W2031057223 @default.
- W2074017816 cites W2032200433 @default.
- W2074017816 cites W2033162367 @default.
- W2074017816 cites W2034340491 @default.
- W2074017816 cites W2039053594 @default.
- W2074017816 cites W2040580021 @default.
- W2074017816 cites W2040891039 @default.
- W2074017816 cites W2043640738 @default.
- W2074017816 cites W2049361027 @default.
- W2074017816 cites W2050554646 @default.
- W2074017816 cites W2054835199 @default.
- W2074017816 cites W2057692691 @default.
- W2074017816 cites W2059099579 @default.
- W2074017816 cites W2065006553 @default.
- W2074017816 cites W2065498897 @default.
- W2074017816 cites W2072208761 @default.
- W2074017816 cites W2072301590 @default.
- W2074017816 cites W2074898309 @default.
- W2074017816 cites W2076333986 @default.
- W2074017816 cites W2078059415 @default.
- W2074017816 cites W2078526277 @default.
- W2074017816 cites W2083245183 @default.
- W2074017816 cites W2084160423 @default.
- W2074017816 cites W2084885369 @default.
- W2074017816 cites W2086038224 @default.
- W2074017816 cites W2087573417 @default.
- W2074017816 cites W2092992881 @default.
- W2074017816 cites W2093682839 @default.
- W2074017816 cites W2094584847 @default.
- W2074017816 cites W2096465161 @default.
- W2074017816 cites W2099468911 @default.
- W2074017816 cites W2102304447 @default.
- W2074017816 cites W2106391833 @default.
- W2074017816 cites W2111521814 @default.
- W2074017816 cites W2115978936 @default.
- W2074017816 cites W2117792884 @default.
- W2074017816 cites W2118608526 @default.
- W2074017816 cites W2118937292 @default.
- W2074017816 cites W2119169932 @default.
- W2074017816 cites W2120100277 @default.
- W2074017816 cites W2121286812 @default.
- W2074017816 cites W2123032740 @default.
- W2074017816 cites W2123564569 @default.
- W2074017816 cites W2124514674 @default.
- W2074017816 cites W2125397535 @default.
- W2074017816 cites W2130374405 @default.
- W2074017816 cites W2135993011 @default.
- W2074017816 cites W2138891173 @default.
- W2074017816 cites W2149118429 @default.
- W2074017816 cites W2151026121 @default.
- W2074017816 cites W2151294425 @default.
- W2074017816 cites W2156626022 @default.
- W2074017816 cites W2158747282 @default.
- W2074017816 cites W2158789461 @default.
- W2074017816 cites W2166355466 @default.
- W2074017816 cites W2166810745 @default.
- W2074017816 cites W2166898061 @default.
- W2074017816 cites W2167197669 @default.
- W2074017816 cites W2167954129 @default.
- W2074017816 cites W2168012760 @default.