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- W2074036521 abstract "The HPV16 E7 oncoprotein and 17β-estradiol are important factors for the induction of premalignant lesions and cervical cancer. The study of these factors is crucial for a better understanding of cervical tumorigenesis. Here, we assessed the global gene expression profiles induced by the HPV16 E7 oncoprotein and/or 17β-estradiol in cervical tissue of FvB and K14E7 transgenic mice. We found that the most dramatic changes in gene expression occurred in K14E7 and FvB groups treated with 17β-estradiol. A large number of differentially expressed genes involved in the immune response were observed in 17β-estradiol treated groups. The E7 oncoprotein mainly affected the expression of genes involved in cellular metabolism. Our microarray data also identified differentially expressed genes that have not previously been reported in cervical cancer. The identification of genes regulated by E7 and 17β-estradiol, provides the basis for further studies on their role in cervical carcinogenesis." @default.
- W2074036521 created "2016-06-24" @default.
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- W2074036521 date "2013-12-01" @default.
- W2074036521 modified "2023-10-18" @default.
- W2074036521 title "Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue" @default.
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- W2074036521 cites W1982152504 @default.
- W2074036521 cites W1982184369 @default.
- W2074036521 cites W1988404672 @default.
- W2074036521 cites W1989812756 @default.
- W2074036521 cites W2011463325 @default.
- W2074036521 cites W2013700000 @default.
- W2074036521 cites W2013763247 @default.
- W2074036521 cites W2024575518 @default.
- W2074036521 cites W2031610000 @default.
- W2074036521 cites W2031795384 @default.
- W2074036521 cites W2033601733 @default.
- W2074036521 cites W2039021968 @default.
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- W2074036521 cites W2061081137 @default.
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- W2074036521 cites W2063357994 @default.
- W2074036521 cites W2063590937 @default.
- W2074036521 cites W2065672772 @default.
- W2074036521 cites W2066332001 @default.
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- W2074036521 cites W2082115514 @default.
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- W2074036521 cites W2086731629 @default.
- W2074036521 cites W2089130754 @default.
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- W2074036521 doi "https://doi.org/10.1016/j.virol.2013.08.036" @default.
- W2074036521 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3982872" @default.
- W2074036521 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24210110" @default.
- W2074036521 hasPublicationYear "2013" @default.
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