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- W2074037165 abstract "Somatosensory stimuli elicit complex cortical responses that are discernible as somatosensory evoked potentials (SEPs) in scalp electroencephalographic recordings. Whereas earlier SEP components, occurring up to 100 ms after stimulus delivery, have been labeled ‘preconscious’, later responses have been associated with stimulus awareness. To date, how far these processes are primarily cortical or comprise additional subcortical operations remains open. Therefore, we recorded thalamic and scalp SEPs evoked by perceived as well as unperceived median nerve stimulation in neurosurgical patients with electrodes implanted into the ventral intermediate nucleus of the thalamus for deep brain stimulation. At stimulation intensities below perceptual threshold, only thalamic SEP components appeared consistently during the first 75 ms after stimulus delivery. Stimulation that was perceived by the patients elicited cortical as well as thalamic SEPs that lasted longer than 75 ms. These results indicate that the thalamus remains active after the primary propagation of a sensory signal to the cortex, and suggest that the transition from elementary to higher-order somatosensory processing is based on thalamo-cortical interactions." @default.
- W2074037165 created "2016-06-24" @default.
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- W2074037165 date "2009-11-01" @default.
- W2074037165 modified "2023-10-02" @default.
- W2074037165 title "Thalamo-cortical processing of near-threshold somatosensory stimuli in humans" @default.
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- W2074037165 doi "https://doi.org/10.1111/j.1460-9568.2009.06970.x" @default.
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