Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074053320> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2074053320 endingPage "298" @default.
- W2074053320 startingPage "293" @default.
- W2074053320 abstract "The possible damaging effect on the kidneys of antihypertensive therapy in aortic coarctation was evaluated experimentally in eighteen canine puppies. Aortic coarctation was carried out in 13 puppies at the age of two months while sham-surgery was carried out on five control puppies. Six coarctated dogs were treated with hydrochlorothiazide, propranolol and prazosin. Antihypertensive therapy was started two months after the operation. Seven coarcted puppies did not receive any treatment. The dogs were followed up for 7 months after which fixation of the kidneys was performed. Antihypertensive therapy decreased blood pressure significantly although the level seen in the control dogs was not attained. There were no signs of deterioration of renal function. Neither light microscopic analysis nor electron microscopy revealed morphological abnormalities in the kidneys of any of the dogs. The present results show that active antihypertensive therapy in experimental coarctation, although not resulting in a normalization but in a significant lowering of blood pressure, is safe and does not cause any morphologic damage in the kidney before corrective surgery. The absence of juxtaglomerular hypertrophy supports the hypothesis that the renin-angiotensin system is not activated in chronic coarctation of aorta." @default.
- W2074053320 created "2016-06-24" @default.
- W2074053320 creator A5013863914 @default.
- W2074053320 creator A5040634343 @default.
- W2074053320 creator A5074473747 @default.
- W2074053320 creator A5080553980 @default.
- W2074053320 creator A5082719079 @default.
- W2074053320 date "1985-03-01" @default.
- W2074053320 modified "2023-10-17" @default.
- W2074053320 title "RENAL STRUCTURE AND FUNCTION IN CHRONIC EXPERIMENTAL AORTIC COARCTATION IN DOGS TREATED WITH ANTIHYPERTENSIVE DRUGS" @default.
- W2074053320 cites W196288178 @default.
- W2074053320 cites W1997733127 @default.
- W2074053320 cites W2023912077 @default.
- W2074053320 cites W2034496674 @default.
- W2074053320 cites W2036117231 @default.
- W2074053320 cites W2042433775 @default.
- W2074053320 cites W2049961787 @default.
- W2074053320 cites W2061538656 @default.
- W2074053320 cites W2075007471 @default.
- W2074053320 cites W2085181720 @default.
- W2074053320 cites W2085200341 @default.
- W2074053320 cites W2086524451 @default.
- W2074053320 cites W2090282293 @default.
- W2074053320 cites W2114758077 @default.
- W2074053320 cites W2143568718 @default.
- W2074053320 cites W2161281429 @default.
- W2074053320 cites W2462865984 @default.
- W2074053320 doi "https://doi.org/10.1111/j.1699-0463.1985.tb03953.x" @default.
- W2074053320 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4050438" @default.
- W2074053320 hasPublicationYear "1985" @default.
- W2074053320 type Work @default.
- W2074053320 sameAs 2074053320 @default.
- W2074053320 citedByCount "0" @default.
- W2074053320 crossrefType "journal-article" @default.
- W2074053320 hasAuthorship W2074053320A5013863914 @default.
- W2074053320 hasAuthorship W2074053320A5040634343 @default.
- W2074053320 hasAuthorship W2074053320A5074473747 @default.
- W2074053320 hasAuthorship W2074053320A5080553980 @default.
- W2074053320 hasAuthorship W2074053320A5082719079 @default.
- W2074053320 hasConcept C126322002 @default.
- W2074053320 hasConcept C126894567 @default.
- W2074053320 hasConcept C141071460 @default.
- W2074053320 hasConcept C159641895 @default.
- W2074053320 hasConcept C164705383 @default.
- W2074053320 hasConcept C2776002628 @default.
- W2074053320 hasConcept C2776467465 @default.
- W2074053320 hasConcept C2779980429 @default.
- W2074053320 hasConcept C2780091579 @default.
- W2074053320 hasConcept C2780361556 @default.
- W2074053320 hasConcept C71924100 @default.
- W2074053320 hasConcept C84393581 @default.
- W2074053320 hasConceptScore W2074053320C126322002 @default.
- W2074053320 hasConceptScore W2074053320C126894567 @default.
- W2074053320 hasConceptScore W2074053320C141071460 @default.
- W2074053320 hasConceptScore W2074053320C159641895 @default.
- W2074053320 hasConceptScore W2074053320C164705383 @default.
- W2074053320 hasConceptScore W2074053320C2776002628 @default.
- W2074053320 hasConceptScore W2074053320C2776467465 @default.
- W2074053320 hasConceptScore W2074053320C2779980429 @default.
- W2074053320 hasConceptScore W2074053320C2780091579 @default.
- W2074053320 hasConceptScore W2074053320C2780361556 @default.
- W2074053320 hasConceptScore W2074053320C71924100 @default.
- W2074053320 hasConceptScore W2074053320C84393581 @default.
- W2074053320 hasIssue "1-6" @default.
- W2074053320 hasLocation W20740533201 @default.
- W2074053320 hasLocation W20740533202 @default.
- W2074053320 hasOpenAccess W2074053320 @default.
- W2074053320 hasPrimaryLocation W20740533201 @default.
- W2074053320 hasRelatedWork W1999434280 @default.
- W2074053320 hasRelatedWork W2001744937 @default.
- W2074053320 hasRelatedWork W2003972033 @default.
- W2074053320 hasRelatedWork W2011100654 @default.
- W2074053320 hasRelatedWork W2091249194 @default.
- W2074053320 hasRelatedWork W2160626360 @default.
- W2074053320 hasRelatedWork W2377006731 @default.
- W2074053320 hasRelatedWork W2428919232 @default.
- W2074053320 hasRelatedWork W2890379 @default.
- W2074053320 hasRelatedWork W3028727574 @default.
- W2074053320 hasVolume "93A" @default.
- W2074053320 isParatext "false" @default.
- W2074053320 isRetracted "false" @default.
- W2074053320 magId "2074053320" @default.
- W2074053320 workType "article" @default.