FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074057716> ?p ?o ?g. }

• W2074057716 endingPage "65" @default.
• W2074057716 startingPage "59" @default.
• W2074057716 abstract "Bioactive papers are usually challenged by four major limitations: sensitivity, selectivity, simplicity and strength (4S). Gold nanoparticles (AuNPs) treated paper has previously been demonstrated as a Surface Enhanced Raman Scattering (SERS) active substrate, capable of addressing the 4S issues. In this study, AuNPs on paper substrate were functionalized by a series of biomolecules to develop a generic SERS platform for antibody–antigen detection. The functionalization steps were performed by taking advantage of the high affinity association between Streptomyces avidinii-derived protein, streptavidin, and biotin. Streptavidin was firstly bound onto the AuNPs treated paper using biotinylated-thiol. Subsequently, desired biotinylated-antibody was bound onto the streptavidin. SERS spectra of each functionalization step were obtained to ensure specific adsorption of the bio-molecules. The binding interaction of the antibody with its specific antigen was detected using SERS. Shifts of Raman band associated with α-helix and β-sheet structures indicated structural modification of the antibody upon interaction with its antigen. Predominant tryptophan and tyrosine residue bands were also detected, confirming the presence of antigen. Reproducible spectral features were quantified as AuNP papers were subjected to different concentrations of antigen; the spectra intensity increased as a function of the antigen concentration. The retention of AuNPs on paper remained constant after all the consecutive washing and functionalization steps. The feasibility of AuNPs paper as a low-cost and generic SERS platform for bio-diagnostic applications was demonstrated." @default.
• W2074057716 created "2016-06-24" @default.
• W2074057716 creator A5069449050 @default.
• W2074057716 creator A5072268281 @default.
• W2074057716 creator A5079119002 @default.
• W2074057716 creator A5088224347 @default.
• W2074057716 date "2013-11-01" @default.
• W2074057716 modified "2023-10-16" @default.
• W2074057716 title "Gold nanoparticles paper as a SERS bio-diagnostic platform" @default.
• W2074057716 cites W1537108777 @default.
• W2074057716 cites W1974235826 @default.
• W2074057716 cites W1999140355 @default.
• W2074057716 cites W2009922859 @default.
• W2074057716 cites W2013477545 @default.
• W2074057716 cites W2021185388 @default.
• W2074057716 cites W2031683089 @default.
• W2074057716 cites W2032696275 @default.
• W2074057716 cites W2034180958 @default.
• W2074057716 cites W2079875315 @default.
• W2074057716 cites W2080511631 @default.
• W2074057716 cites W2083445427 @default.
• W2074057716 cites W2085234074 @default.
• W2074057716 cites W2092049851 @default.
• W2074057716 cites W2092055204 @default.
• W2074057716 cites W2092293839 @default.
• W2074057716 cites W2109311842 @default.
• W2074057716 cites W2115029038 @default.
• W2074057716 cites W2146367394 @default.
• W2074057716 cites W2171612604 @default.
• W2074057716 cites W2313933366 @default.
• W2074057716 cites W2325022826 @default.
• W2074057716 cites W3131735448 @default.
• W2074057716 doi "https://doi.org/10.1016/j.jcis.2013.07.051" @default.
• W2074057716 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23978290" @default.
• W2074057716 hasPublicationYear "2013" @default.
• W2074057716 type Work @default.
• W2074057716 sameAs 2074057716 @default.
• W2074057716 citedByCount "41" @default.
• W2074057716 countsByYear W20740577162014 @default.
• W2074057716 countsByYear W20740577162015 @default.
• W2074057716 countsByYear W20740577162016 @default.
• W2074057716 countsByYear W20740577162017 @default.
• W2074057716 countsByYear W20740577162018 @default.
• W2074057716 countsByYear W20740577162019 @default.
• W2074057716 countsByYear W20740577162020 @default.
• W2074057716 countsByYear W20740577162021 @default.
• W2074057716 countsByYear W20740577162022 @default.
• W2074057716 countsByYear W20740577162023 @default.
• W2074057716 crossrefType "journal-article" @default.
• W2074057716 hasAuthorship W2074057716A5069449050 @default.
• W2074057716 hasAuthorship W2074057716A5072268281 @default.
• W2074057716 hasAuthorship W2074057716A5079119002 @default.
• W2074057716 hasAuthorship W2074057716A5088224347 @default.
• W2074057716 hasConcept C104819515 @default.
• W2074057716 hasConcept C111368507 @default.
• W2074057716 hasConcept C115537861 @default.
• W2074057716 hasConcept C120665830 @default.
• W2074057716 hasConcept C121332964 @default.
• W2074057716 hasConcept C127313418 @default.
• W2074057716 hasConcept C138631740 @default.
• W2074057716 hasConcept C147483822 @default.
• W2074057716 hasConcept C147789679 @default.
• W2074057716 hasConcept C155672457 @default.
• W2074057716 hasConcept C171250308 @default.
• W2074057716 hasConcept C176406525 @default.
• W2074057716 hasConcept C185592680 @default.
• W2074057716 hasConcept C192562407 @default.
• W2074057716 hasConcept C195616568 @default.
• W2074057716 hasConcept C204628709 @default.
• W2074057716 hasConcept C21951064 @default.
• W2074057716 hasConcept C2776190903 @default.
• W2074057716 hasConcept C2777289219 @default.
• W2074057716 hasConcept C2778204606 @default.
• W2074057716 hasConcept C40003534 @default.
• W2074057716 hasConcept C49853544 @default.
• W2074057716 hasConcept C54355233 @default.
• W2074057716 hasConcept C55493867 @default.
• W2074057716 hasConcept C86803240 @default.
• W2074057716 hasConcept C9086966 @default.
• W2074057716 hasConceptScore W2074057716C104819515 @default.
• W2074057716 hasConceptScore W2074057716C111368507 @default.
• W2074057716 hasConceptScore W2074057716C115537861 @default.
• W2074057716 hasConceptScore W2074057716C120665830 @default.
• W2074057716 hasConceptScore W2074057716C121332964 @default.
• W2074057716 hasConceptScore W2074057716C127313418 @default.
• W2074057716 hasConceptScore W2074057716C138631740 @default.
• W2074057716 hasConceptScore W2074057716C147483822 @default.
• W2074057716 hasConceptScore W2074057716C147789679 @default.
• W2074057716 hasConceptScore W2074057716C155672457 @default.
• W2074057716 hasConceptScore W2074057716C171250308 @default.
• W2074057716 hasConceptScore W2074057716C176406525 @default.
• W2074057716 hasConceptScore W2074057716C185592680 @default.
• W2074057716 hasConceptScore W2074057716C192562407 @default.
• W2074057716 hasConceptScore W2074057716C195616568 @default.
• W2074057716 hasConceptScore W2074057716C204628709 @default.
• W2074057716 hasConceptScore W2074057716C21951064 @default.
• W2074057716 hasConceptScore W2074057716C2776190903 @default.
• W2074057716 hasConceptScore W2074057716C2777289219 @default.

• next