FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074080783> ?p ?o ?g. }

• W2074080783 endingPage "352" @default.
• W2074080783 startingPage "347" @default.
• W2074080783 abstract "Primary mediastinal seminoma is an uncommon neoplasm, the optimal management of which is still debated. Radiotherapy produces a 65% disease-free survival rate. We assess whether these results have been improved with the advent of cisplatin-based chemotherapy. Data from 14 patients treated at the Institut Gustave-Roussy were reviewed. 9 had received cisplatin-based chemotherapy (Group 1): their outcome was compared with that of 5 patients treated with radiotherapy without chemotherapy (Group 2). We also reviewed data from the English literature using strict criteria, and report results concerning patients who received cisplatin-based chemotherapy and those who received radiotherapy. 8 of the 9 patients (89%) in Group 1 are long-term disease-free survivors and only 3 of 5 patients in Group 2. The patient who died in Group 1 was the only one who refused surgical resection of residual masses after chemotherapy. The review of the literature revealed that 59 of 68 (87%) patients initially managed with cisplatin- or carboplatin-based chemotherapy and for whom sufficient data are available, are long-term survivors and free of disease. Some of these patients had also received radiotherapy. Only 64 of 103 (62%) treated with thoracic radiotherapy without chemotherapy were long-term disease-free survivors. The disease-free survival rate of 51 patients who received cisplatin-based chemotherapy (excluding those who received carboplatin) was 86%. The difference in survival between patients administered cisplatin-based chemotherapy and those who underwent radiotherapy is apparently not due to unbalanced prognostic factors, the effect of time or non-specific medical management. We conclude that cisplatin-based chemotherapy allows long-term disease-free survival in approximately 85% of patients. These results seem to be higher than those obtained without cisplatin-based chemotherapy. However, a randomised study is required for definitive conclusions, but it is very unlikely that such a study will be performed due to the rarity of this neoplasm. Another alternative would be a meta-analysis based on individual data." @default.
• W2074080783 created "2016-06-24" @default.
• W2074080783 creator A5007779528 @default.
• W2074080783 creator A5035754430 @default.
• W2074080783 creator A5043616693 @default.
• W2074080783 creator A5055791669 @default.
• W2074080783 creator A5059228974 @default.
• W2074080783 creator A5066325139 @default.
• W2074080783 creator A5082893702 @default.
• W2074080783 creator A5083341347 @default.
• W2074080783 creator A5090993023 @default.
• W2074080783 date "1998-02-01" @default.
• W2074080783 modified "2023-09-25" @default.
• W2074080783 title "Initial management of primary mediastinal seminoma: radiotherapy or cisplatin-based chemotherapy?" @default.
• W2074080783 cites W1494111313 @default.
• W2074080783 cites W1838921188 @default.
• W2074080783 cites W1840867835 @default.
• W2074080783 cites W1954191290 @default.
• W2074080783 cites W1959995982 @default.
• W2074080783 cites W1965912934 @default.
• W2074080783 cites W1968050199 @default.
• W2074080783 cites W1973599693 @default.
• W2074080783 cites W1976217486 @default.
• W2074080783 cites W1986743129 @default.
• W2074080783 cites W2007810237 @default.
• W2074080783 cites W2012218081 @default.
• W2074080783 cites W2012796096 @default.
• W2074080783 cites W2014451840 @default.
• W2074080783 cites W2017317707 @default.
• W2074080783 cites W2021009044 @default.
• W2074080783 cites W2025689009 @default.
• W2074080783 cites W2030208343 @default.
• W2074080783 cites W2038242919 @default.
• W2074080783 cites W2045732801 @default.
• W2074080783 cites W2048537360 @default.
• W2074080783 cites W2049374435 @default.
• W2074080783 cites W2051026412 @default.
• W2074080783 cites W2053816430 @default.
• W2074080783 cites W2054235025 @default.
• W2074080783 cites W2061295542 @default.
• W2074080783 cites W2061684524 @default.
• W2074080783 cites W2082247446 @default.
• W2074080783 cites W2083384747 @default.
• W2074080783 cites W2093193602 @default.
• W2074080783 cites W2101458725 @default.
• W2074080783 cites W2118266677 @default.
• W2074080783 cites W2118974991 @default.
• W2074080783 cites W2161996409 @default.
• W2074080783 cites W2263143764 @default.
• W2074080783 cites W2313706276 @default.
• W2074080783 cites W2409528816 @default.
• W2074080783 cites W2442432154 @default.
• W2074080783 cites W4253993532 @default.
• W2074080783 doi "https://doi.org/10.1016/s0959-8049(97)10021-1" @default.
• W2074080783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9640220" @default.
• W2074080783 hasPublicationYear "1998" @default.
• W2074080783 type Work @default.
• W2074080783 sameAs 2074080783 @default.
• W2074080783 citedByCount "28" @default.
• W2074080783 countsByYear W20740807832012 @default.
• W2074080783 countsByYear W20740807832013 @default.
• W2074080783 countsByYear W20740807832014 @default.
• W2074080783 countsByYear W20740807832015 @default.
• W2074080783 countsByYear W20740807832017 @default.
• W2074080783 countsByYear W20740807832020 @default.
• W2074080783 countsByYear W20740807832021 @default.
• W2074080783 countsByYear W20740807832022 @default.
• W2074080783 crossrefType "journal-article" @default.
• W2074080783 hasAuthorship W2074080783A5007779528 @default.
• W2074080783 hasAuthorship W2074080783A5035754430 @default.
• W2074080783 hasAuthorship W2074080783A5043616693 @default.
• W2074080783 hasAuthorship W2074080783A5055791669 @default.
• W2074080783 hasAuthorship W2074080783A5059228974 @default.
• W2074080783 hasAuthorship W2074080783A5066325139 @default.
• W2074080783 hasAuthorship W2074080783A5082893702 @default.
• W2074080783 hasAuthorship W2074080783A5083341347 @default.
• W2074080783 hasAuthorship W2074080783A5090993023 @default.
• W2074080783 hasConcept C126322002 @default.
• W2074080783 hasConcept C141071460 @default.
• W2074080783 hasConcept C143998085 @default.
• W2074080783 hasConcept C2776694085 @default.
• W2074080783 hasConcept C2778074268 @default.
• W2074080783 hasConcept C2778239845 @default.
• W2074080783 hasConcept C2781451048 @default.
• W2074080783 hasConcept C509974204 @default.
• W2074080783 hasConcept C71924100 @default.
• W2074080783 hasConceptScore W2074080783C126322002 @default.
• W2074080783 hasConceptScore W2074080783C141071460 @default.
• W2074080783 hasConceptScore W2074080783C143998085 @default.
• W2074080783 hasConceptScore W2074080783C2776694085 @default.
• W2074080783 hasConceptScore W2074080783C2778074268 @default.
• W2074080783 hasConceptScore W2074080783C2778239845 @default.
• W2074080783 hasConceptScore W2074080783C2781451048 @default.
• W2074080783 hasConceptScore W2074080783C509974204 @default.
• W2074080783 hasConceptScore W2074080783C71924100 @default.
• W2074080783 hasIssue "3" @default.
• W2074080783 hasLocation W20740807831 @default.
• W2074080783 hasLocation W20740807832 @default.

• next