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- W2074093877 abstract "Yeast has been a valuable model to study replicative and chronological ageing processes. Replicative ageing is defined by the number of daughter cells a mother can give birth to and hence reflects the ageing situation in proliferating cells, whereas chronological ageing is widely accepted as a model for postmitotic tissue ageing. Since both ageing forms end in yeast programmed death (necrotic and apoptotic), and abrogation of cell death by deletion of the apoptotic machinery or diminishment of oxidative radicals leads to longevity, apoptosis and ageing seem closely connected. This review focuses on ageing as a physiological way to induce yeast apoptosis, which unexpectedly defines apoptosis as a pro- and not an anti-ageing mechanism." @default.
- W2074093877 created "2016-06-24" @default.
- W2074093877 creator A5074996521 @default.
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- W2074093877 date "2008-10-01" @default.
- W2074093877 modified "2023-10-17" @default.
- W2074093877 title "Apoptotic death of ageing yeast" @default.
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- W2074093877 doi "https://doi.org/10.1016/j.exger.2008.08.044" @default.
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