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- W207410295 abstract "Cervical cancer is the fourth most common cancer affecting women worldwide. Radical hysterectomy with pelvic lymphadenectomy with or without adjuvant radiation therapy is used as primary therapy for IB stage carcinoma of the cervix. The aim of this study was to compare the complications and quality of life of patients with stage IB1 cervical carcinoma treated by surgery or combined surgery and adjuvant radiotherapy. In a prospective case-control study 49 patients diagnosed with a cervical cancer were included - 37 patients receiving adjuvant radiotherapy in the study group and 12 patients without radiotherapy in the control group that were undergoing surgical treatment in Riga Eastern Clinical university hospital between January 2011 and December 2012. Mean age was higher in patients who received adjuvant radiotherapy in comparison to patients who received only surgical treatment – 49,76±11,54 vs. 40,08±9,59 years (p=0,012). Higher stromal invasion was in adjuvant radiotherapy group comparing to surgical group- 12,44±5,05 vs. 8,27±4,32 mm (p=0,02). Patients who received adjuvant radiotherapy more often experienced symptoms related to the radiation influence on gastrointestinal tract and urinary system.Diarrhea during the treatment was statistically higher in adjuvant radiotherapy group (p<0,001). In addition, dysuria after the therapy (p=0,065), dysuria at the time of interview (p=0,078) and legs edema at the time of interview (p=0,080) were more often observed in adjuvant radiotherapy group. No differences between groups were observed for constipation (p=0,123), legs edema after the treatment (p=0,305) and diarrhea at the time of interview (p=0,634)." @default.
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- W207410295 date "2014-05-19" @default.
- W207410295 modified "2023-09-24" @default.
- W207410295 title "The Influence of Adjuvant Radiotherapy on Physical Symptoms and Quality of Life In IB1 Stage Cervical Cancer Patients" @default.
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