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- W2074133029 abstract "It has been demonstrated that the presence of cysteamine during irradiation brings about the reduction of UV-induced chromosome breaks in BU-substituted mammalian cells. Cysteamine had no or considerably less effect on the UV-induced chromosome breaks in non-BU-substituted cells, nor did it enhance the resumption of UV-induced inhibition of DNA synthesis in BU-substituted cells. The results have been interpreted to indicate that BUdR sensitization of UV-induced chromosomal damage in mammalian cells is due to the nature of the BU photoproduct and not to BU photoproduct inhibition of a rejoining process. Also, UV-induced photoproducts in BU-substituted cells that cause chromosome breaks might not be those that cause UV inhibition of DNA synthesis." @default.
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- W2074133029 date "1967-10-01" @default.
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- W2074133029 title "Inhibition of Ultraviolet-Induced Chromosome Breaks by Cysteamine in 5-Bromouracil-Substituted Mammalian Cells" @default.
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- W2074133029 doi "https://doi.org/10.2307/3572218" @default.
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