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- W2074148908 abstract "Abstract Schisandra chinensis (Turcz.) Baill. (SCTB) is a functional, economical and medicinal herb that has numerous medicinal and nutritional properties. The present study was carried out to investigate its inhibitory activities against protein tyrosine phosphatase 1B (PTP1B) and α -glucosidase. The extracts and compounds isolated from petroleum ether (PE) extract were further tested for their PTP1B and α -glucosidase inhibitory activities. The data showed that the anti-diabetic activity of SCTB is attributable to the PE (IC 50 = 1.77 ± 0.20 μg/mL) and EtOAc (IC 50 = 1.04 ± 0.20 μg/mL) extracts as well as compounds 1 (IC 50 = 2.36 ± 0.20 μM) and 4 (IC 50 = 9.78 ± 0.10 μM) that were compared with the positive controls NaVO 4 (IC 50 = 22 ± 0.20 μM) and acarbose (IC 50 = 2.10 ± 0.10 μg/mL), respectively. These results demonstrate that the stems of SCTB are useful as potential functional food ingredients for the prevention and treatment of type-2 diabetes." @default.
- W2074148908 created "2016-06-24" @default.
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- W2074148908 date "2014-07-01" @default.
- W2074148908 modified "2023-10-17" @default.
- W2074148908 title "Protein tyrosine phosphatase 1B (PTP1B) and α-glucosidase inhibitory activities of Schisandra chinensis (Turcz.) Baill" @default.
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- W2074148908 doi "https://doi.org/10.1016/j.jff.2014.04.017" @default.
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