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- W2074157027 abstract "The need of a specific defence mechanism against intracellular pathogens is proposed to have arisen very early in evolution, perhaps already in protozoa, e.g. amoebae. The phagocytic machinery of amoebae lends itself as a possible starting point for the evolution of such a mechanism. The hypothetical evolutionary pathway described here has been constructed to demonstrate the feasibility of developing a defence system against pathogens in the amoeba, which bears resemblances to contemporary cell-mediated immunity, and can thus be considered as its ancestor." @default.
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- W2074157027 date "2008-02-11" @default.
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- W2074157027 title "Evolutionary Origin of the Immune System: A Dialogue with Rod Langman" @default.
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- W2074157027 doi "https://doi.org/10.1111/j.1365-3083.2008.02075.x" @default.
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