Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074203008> ?p ?o ?g. }
- W2074203008 endingPage "192" @default.
- W2074203008 startingPage "187" @default.
- W2074203008 abstract "Reaction of chloro-bridged dinuclear palladacycles, [Pd2{(C,N)-C6H4CH2NH(R)}2(μ-Cl)2] (R = Et (1a); R = t-Bu (1b)) with pyridine and PPh3 in the 1:2 M ratio at room temperature was used to prepare the mononuclear complexes, [Pd(C,N)-C6H4CH2NH(R)Cl(L)] (R = Et and L = Py (2a); R = t-Bu and L = PPh3 (2b)). Bridged biphosphinic palladacycle, [Pd2(C,N-dmba)2(μ-dppe)(Cl)2] (2c), (where dmba = N,N-dimethylbenzylamine and dppe = 1,2-bis(diphenylphosphino)ethane) has been also synthesized. The complexes were fully characterized by elemental analysis, IR and NMR spectroscopies. In addition, the solid structures of palladacycles 2a and 2c were studied by single-crystal X-ray crystallography. In vitro cytotoxicity assays of the cyclopalladated complexes, (2a−2c) and cisplatin were evaluated against the Hela (human cervix carcinoma), HT-29 (colon cancer cell line), K562 (leukemia cancer cell line) and MDA-MB-468 (human breast carcinoma). The complexes 2a−2c display IC50 values in a μM range better than that of the antitumor drug cisplatin." @default.
- W2074203008 created "2016-06-24" @default.
- W2074203008 creator A5004478122 @default.
- W2074203008 creator A5012798532 @default.
- W2074203008 creator A5023138424 @default.
- W2074203008 creator A5048265478 @default.
- W2074203008 creator A5048528640 @default.
- W2074203008 date "2013-02-01" @default.
- W2074203008 modified "2023-10-16" @default.
- W2074203008 title "Dinuclear bridged biphosphinic and mononuclear cyclopalladated complexes of benzylamines: Synthesis, structural characterization and antitumor activity" @default.
- W2074203008 cites W1965042700 @default.
- W2074203008 cites W1988785281 @default.
- W2074203008 cites W1993584747 @default.
- W2074203008 cites W1999292430 @default.
- W2074203008 cites W2003613057 @default.
- W2074203008 cites W2006815847 @default.
- W2074203008 cites W2007201130 @default.
- W2074203008 cites W2010777100 @default.
- W2074203008 cites W2011033166 @default.
- W2074203008 cites W2011598571 @default.
- W2074203008 cites W2012296532 @default.
- W2074203008 cites W2014004239 @default.
- W2074203008 cites W2022581325 @default.
- W2074203008 cites W2032313197 @default.
- W2074203008 cites W2037666434 @default.
- W2074203008 cites W2046361778 @default.
- W2074203008 cites W2059024497 @default.
- W2074203008 cites W2064569784 @default.
- W2074203008 cites W2069580292 @default.
- W2074203008 cites W2070481472 @default.
- W2074203008 cites W2072208433 @default.
- W2074203008 cites W2073056302 @default.
- W2074203008 cites W2075010434 @default.
- W2074203008 cites W2075346893 @default.
- W2074203008 cites W2075540003 @default.
- W2074203008 cites W2084800847 @default.
- W2074203008 cites W2088267724 @default.
- W2074203008 cites W2107734878 @default.
- W2074203008 cites W2114918609 @default.
- W2074203008 cites W2128972757 @default.
- W2074203008 cites W2130177169 @default.
- W2074203008 cites W2142597103 @default.
- W2074203008 cites W2162683363 @default.
- W2074203008 cites W2163464317 @default.
- W2074203008 cites W2201931770 @default.
- W2074203008 cites W2331176150 @default.
- W2074203008 cites W327629993 @default.
- W2074203008 doi "https://doi.org/10.1016/j.poly.2012.11.002" @default.
- W2074203008 hasPublicationYear "2013" @default.
- W2074203008 type Work @default.
- W2074203008 sameAs 2074203008 @default.
- W2074203008 citedByCount "32" @default.
- W2074203008 countsByYear W20742030082014 @default.
- W2074203008 countsByYear W20742030082015 @default.
- W2074203008 countsByYear W20742030082016 @default.
- W2074203008 countsByYear W20742030082017 @default.
- W2074203008 countsByYear W20742030082018 @default.
- W2074203008 countsByYear W20742030082019 @default.
- W2074203008 countsByYear W20742030082020 @default.
- W2074203008 countsByYear W20742030082021 @default.
- W2074203008 countsByYear W20742030082022 @default.
- W2074203008 countsByYear W20742030082023 @default.
- W2074203008 crossrefType "journal-article" @default.
- W2074203008 hasAuthorship W2074203008A5004478122 @default.
- W2074203008 hasAuthorship W2074203008A5012798532 @default.
- W2074203008 hasAuthorship W2074203008A5023138424 @default.
- W2074203008 hasAuthorship W2074203008A5048265478 @default.
- W2074203008 hasAuthorship W2074203008A5048528640 @default.
- W2074203008 hasConcept C104317684 @default.
- W2074203008 hasConcept C109316439 @default.
- W2074203008 hasConcept C115624301 @default.
- W2074203008 hasConcept C141071460 @default.
- W2074203008 hasConcept C155647269 @default.
- W2074203008 hasConcept C185592680 @default.
- W2074203008 hasConcept C202751555 @default.
- W2074203008 hasConcept C2776694085 @default.
- W2074203008 hasConcept C2777366897 @default.
- W2074203008 hasConcept C2778239845 @default.
- W2074203008 hasConcept C2778938436 @default.
- W2074203008 hasConcept C2779485729 @default.
- W2074203008 hasConcept C55493867 @default.
- W2074203008 hasConcept C555283112 @default.
- W2074203008 hasConcept C71240020 @default.
- W2074203008 hasConcept C71924100 @default.
- W2074203008 hasConcept C8010536 @default.
- W2074203008 hasConceptScore W2074203008C104317684 @default.
- W2074203008 hasConceptScore W2074203008C109316439 @default.
- W2074203008 hasConceptScore W2074203008C115624301 @default.
- W2074203008 hasConceptScore W2074203008C141071460 @default.
- W2074203008 hasConceptScore W2074203008C155647269 @default.
- W2074203008 hasConceptScore W2074203008C185592680 @default.
- W2074203008 hasConceptScore W2074203008C202751555 @default.
- W2074203008 hasConceptScore W2074203008C2776694085 @default.
- W2074203008 hasConceptScore W2074203008C2777366897 @default.
- W2074203008 hasConceptScore W2074203008C2778239845 @default.
- W2074203008 hasConceptScore W2074203008C2778938436 @default.
- W2074203008 hasConceptScore W2074203008C2779485729 @default.
- W2074203008 hasConceptScore W2074203008C55493867 @default.