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- W207421023 abstract "Publisher SummaryThis chapter discusses ventilation–perfusion inhomogeneity and efficiency of alveolar gas exchange. Methods have been developed for deriving a great deal of information about the distributions of ventilation–perfusion ratios, which must be present in life in both the normal and diseased lung. One way of approaching a distribution of ventilation–perfusion ratios is to build it up from separate distributions of ventilation and blood flow. Various indices such as the alveolar–arterial PO2 difference, physiologic dead space, and physiologic shunt have been used very successfully to assess the impairment of gas exchange caused by ventilation–perfusion inequality in normal and diseased lungs. The effect of this pure ventilation–perfusion inequality is to decrease both the oxygen uptake and carbon dioxide output of the lung. Analysis of the behavior of gases of different solubilities in lung models with ventilation–perfusion inequality indicates that gases of moderate solubility always have their transfer impaired most by ventilation–perfusion inequality and that gases of very low or very high solubility are less affected." @default.
- W207421023 created "2016-06-24" @default.
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- W207421023 date "1981-01-01" @default.
- W207421023 modified "2023-09-27" @default.
- W207421023 title "VENTILATION-PERFUSION INHOMOGENEITY AND EFFICIENCY OF ALVEOLAR GAS EXCHANGE" @default.
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- W207421023 doi "https://doi.org/10.1016/b978-0-08-026823-1.50029-6" @default.
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