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• W2074233915 startingPage "217" @default.
• W2074233915 abstract "We investigated the effects of genotype (two different clones) and multigenerational Cd-exposure history on Cd toxicity, individual fitness, and biokinetics in populations of a freshwater cladoceran Daphnia magna. The adults of the tolerant (T) clone had longer mean-survival-time than the sensitive (S) clone in both control groups (without Cd-exposure) and continuous Cd-exposure groups, but the two clones showed comparable resistances to acute Cd stress in the recovery groups. The body concentration of metallothionein (MT) played a critical role in handling Cd stress, which mainly accounted for the significant difference between the two clones in terms of survival distribution. High comparability of these two clones in individual fitness parameters and biokinetics suggested that these parameters are unlikely driven by genetic variation. For each specific clone, continuous Cd-exposure inhibited the animal growth, elevated the MT induction, and increased the Cd uptake rate (ingestion rate, assimilation efficiency from dietary phase, and uptake rate from dissolved phase), all of which enhanced the weight-specific Cd accumulation in daphnids’ bodies. The strong dependence of biokinetic parameters on environmental factors (e.g., food concentrations, pH, dissolved or dietary metal concentration, and metal exposure histories) rather than on genotypes implied the great potential of using biokinetics in inter-lab comparisons and environmental risk assessments." @default.
• W2074233915 created "2016-06-24" @default.
• W2074233915 creator A5033511296 @default.
• W2074233915 creator A5066308891 @default.
• W2074233915 date "2006-03-01" @default.
• W2074233915 modified "2023-09-30" @default.
• W2074233915 title "Comparison between two clones of Daphnia magna: Effects of multigenerational cadmium exposure on toxicity, individual fitness, and biokinetics" @default.
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• W2074233915 doi "https://doi.org/10.1016/j.aquatox.2005.10.003" @default.
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• W2074233915 hasPublicationYear "2006" @default.
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