FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074242092> ?p ?o ?g. }

• W2074242092 endingPage "344" @default.
• W2074242092 startingPage "338" @default.
• W2074242092 abstract "One of the main goals of immunotherapy of allergic diseases is the down-regulation of the type I hypersensitivity reaction. We investigated in this study the effect of oral administration of varying doses (0.25, 1.0, 4.0 and 10 mg) of dust mite extract (Dermatophagoides pteronyssinus, Dp) in sensitized A/Sn mice. A marked decrease of the allergen-specific immunoglobulin E (IgE) response was observed with all antigen doses. The mice orally tolerized with low Dp dose (0.25 mg) had a significant decrease in the total serum IgE and in the immunoglobulin G1 (IgG1), IgG2a and IgG2b antibody levels. The higher Dp dose (10.0 mg), however, enhanced the IgG1 antibody response, suggesting the stimulation of a pre-existing immune response of the sensitized animals. Animals fed with the low Dp dose had a significant decrease in the frequency of interleukin-4 (IL-4) secreting cells. These animals also showed a significant decrease in the frequency of Dp-specific IgE- and IgG1-positive plasma cells. Our data suggest that feeding dust mite extract to Dp-sensitized mice down-regulates the development of type I hypersensitivity, by inhibition of the T helper 2 response." @default.
• W2074242092 created "2016-06-24" @default.
• W2074242092 creator A5001612389 @default.
• W2074242092 creator A5045814232 @default.
• W2074242092 creator A5059469358 @default.
• W2074242092 creator A5061419619 @default.
• W2074242092 creator A5072112019 @default.
• W2074242092 creator A5088304865 @default.
• W2074242092 date "1999-11-01" @default.
• W2074242092 modified "2023-10-18" @default.
• W2074242092 title "Low dose of orally administered antigen down-regulates the T helper type 2-response in a murine model of dust mite hypersensitivity" @default.
• W2074242092 cites W1539696212 @default.
• W2074242092 cites W1586162124 @default.
• W2074242092 cites W1839032935 @default.
• W2074242092 cites W1905494569 @default.
• W2074242092 cites W1968274103 @default.
• W2074242092 cites W1976323650 @default.
• W2074242092 cites W1988317772 @default.
• W2074242092 cites W1992985178 @default.
• W2074242092 cites W2002003044 @default.
• W2074242092 cites W2008361206 @default.
• W2074242092 cites W2014964336 @default.
• W2074242092 cites W2019398337 @default.
• W2074242092 cites W2022410707 @default.
• W2074242092 cites W2053206245 @default.
• W2074242092 cites W2054930447 @default.
• W2074242092 cites W2069065778 @default.
• W2074242092 cites W2075376701 @default.
• W2074242092 cites W2075963617 @default.
• W2074242092 cites W2086547881 @default.
• W2074242092 cites W2128707261 @default.
• W2074242092 cites W2159281402 @default.
• W2074242092 cites W2163682172 @default.
• W2074242092 cites W2172174516 @default.
• W2074242092 cites W2396213430 @default.
• W2074242092 cites W2416307862 @default.
• W2074242092 cites W247969383 @default.
• W2074242092 cites W61923048 @default.
• W2074242092 doi "https://doi.org/10.1046/j.1365-2567.1999.00869.x" @default.
• W2074242092 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2326944" @default.
• W2074242092 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10583591" @default.
• W2074242092 hasPublicationYear "1999" @default.
• W2074242092 type Work @default.
• W2074242092 sameAs 2074242092 @default.
• W2074242092 citedByCount "16" @default.
• W2074242092 countsByYear W20742420922012 @default.
• W2074242092 countsByYear W20742420922018 @default.
• W2074242092 crossrefType "journal-article" @default.
• W2074242092 hasAuthorship W2074242092A5001612389 @default.
• W2074242092 hasAuthorship W2074242092A5045814232 @default.
• W2074242092 hasAuthorship W2074242092A5059469358 @default.
• W2074242092 hasAuthorship W2074242092A5061419619 @default.
• W2074242092 hasAuthorship W2074242092A5072112019 @default.
• W2074242092 hasAuthorship W2074242092A5088304865 @default.
• W2074242092 hasBestOaLocation W20742420922 @default.
• W2074242092 hasConcept C126322002 @default.
• W2074242092 hasConcept C141105273 @default.
• W2074242092 hasConcept C147483822 @default.
• W2074242092 hasConcept C159654299 @default.
• W2074242092 hasConcept C170493617 @default.
• W2074242092 hasConcept C203014093 @default.
• W2074242092 hasConcept C207480886 @default.
• W2074242092 hasConcept C24998067 @default.
• W2074242092 hasConcept C2779711295 @default.
• W2074242092 hasConcept C2779779143 @default.
• W2074242092 hasConcept C2780510475 @default.
• W2074242092 hasConcept C59822182 @default.
• W2074242092 hasConcept C71924100 @default.
• W2074242092 hasConcept C86803240 @default.
• W2074242092 hasConcept C8891405 @default.
• W2074242092 hasConceptScore W2074242092C126322002 @default.
• W2074242092 hasConceptScore W2074242092C141105273 @default.
• W2074242092 hasConceptScore W2074242092C147483822 @default.
• W2074242092 hasConceptScore W2074242092C159654299 @default.
• W2074242092 hasConceptScore W2074242092C170493617 @default.
• W2074242092 hasConceptScore W2074242092C203014093 @default.
• W2074242092 hasConceptScore W2074242092C207480886 @default.
• W2074242092 hasConceptScore W2074242092C24998067 @default.
• W2074242092 hasConceptScore W2074242092C2779711295 @default.
• W2074242092 hasConceptScore W2074242092C2779779143 @default.
• W2074242092 hasConceptScore W2074242092C2780510475 @default.
• W2074242092 hasConceptScore W2074242092C59822182 @default.
• W2074242092 hasConceptScore W2074242092C71924100 @default.
• W2074242092 hasConceptScore W2074242092C86803240 @default.
• W2074242092 hasConceptScore W2074242092C8891405 @default.
• W2074242092 hasIssue "3" @default.
• W2074242092 hasLocation W20742420921 @default.
• W2074242092 hasLocation W20742420922 @default.
• W2074242092 hasLocation W20742420923 @default.
• W2074242092 hasOpenAccess W2074242092 @default.
• W2074242092 hasPrimaryLocation W20742420921 @default.
• W2074242092 hasRelatedWork W1544560791 @default.
• W2074242092 hasRelatedWork W1971608229 @default.
• W2074242092 hasRelatedWork W1998315141 @default.
• W2074242092 hasRelatedWork W2021568655 @default.
• W2074242092 hasRelatedWork W2026326148 @default.
• W2074242092 hasRelatedWork W2155035360 @default.
• W2074242092 hasRelatedWork W2370886589 @default.

• next