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- W2074277237 abstract "Depolarization of isolated myocytes for several seconds produces a maintained, tonic component of tension. We have found that this is abolished by 5 mM-Ni2+. Furthermore if Ni2+ is applied after the tonic contraction has developed then its relaxation is prevented. These results are consistent with the hypothesis that Ni2+ inhibits Na+-Ca2+ exchange. Finally, also consistent with an inhibition of Na+-Ca2+ exchange, Ni2+ abolishes the transient inward current while having no effect on the underlying change of [Ca2+]i." @default.
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- W2074277237 date "1988-11-12" @default.
- W2074277237 modified "2023-10-16" @default.
- W2074277237 title "THE EFFECTS OF NICKEL ON CONTRACTION AND MEMBRANE CURRENT IN ISOLATED RAT MYOCYTES" @default.
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- W2074277237 doi "https://doi.org/10.1113/expphysiol.1988.sp003213" @default.
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