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- W2074303399 abstract "We characterized a novel group of HCV variants that are genetically related but distinct from each other belonging to genotype 6 (HCV-6). From 26 infected Austronesian-descended aborigines on Hainan Island, China, HCV sequences were determined followed by genetic analyses. Six nearly full-length genomes and 20 E1 sequences of HCV were obtained, which differ from each other and from all known HCV lineages by nucleotides above the intra-subtype level of 13%. Together with subtypes 6g and 6w, they constitute a phylogenetic group sharing a common ancestor dating from the end of the 12th century.Our data indicate the maintenance of an isolated HCV-6 indigenous circulation on Hainan Island at least for six centuries." @default.
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- W2074303399 date "2014-09-01" @default.
- W2074303399 modified "2023-09-27" @default.
- W2074303399 title "Conservation in China of a novel group of HCV variants dating to six centuries ago" @default.
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- W2074303399 doi "https://doi.org/10.1016/j.virol.2014.06.011" @default.
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