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- W2074320381 abstract "Introgression is the permanent incorporation of genes from one population into another through hybridization and backcrossing. It is currently of particular concern as a possible mechanism for the spread of modified crop genes to wild populations. The hazard rate is the probability per time unit that such an escape takes place, given that it has not happened before. It is a quantitative measure of introgression risk that takes the stochastic elements inherent in introgression processes into account. We present a methodology to calculate the hazard rate for situations with time-varying gene flow from a crop to a large recipient wild population. As an illustration, several types of time-inhomogeneity are examined, including deterministic periodicity as well as random variation. Furthermore, we examine the effects of an extended fitness bottleneck of hybrids and backcrosses in combination with time-varying gene flow. It is found that bottlenecks decrease the hazard rate, but also slow down and delay its changes in reaction to changes in gene flow. Furthermore, we find that random variation in gene flow generates a lower hazard rate than analogous deterministic variation. We discuss the implications of our findings for crop management and introgression risk assessment." @default.
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- W2074320381 date "2012-06-01" @default.
- W2074320381 modified "2023-10-18" @default.
- W2074320381 title "Quantifying time-inhomogeneous stochastic introgression processes with hazard rates" @default.
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- W2074320381 doi "https://doi.org/10.1016/j.tpb.2011.11.006" @default.
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