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- W2074363716 abstract "This was a retrospective study of 126 primary pleomorphic adenomas to correlate capsular characteristics with tumour histopathology in relation to current surgical debate (parotidectomy versus local excision). Capsular thickness was measured by micrometry and tumours classified into subtypes (1-4). Evidence of fine needle aspiration damage (needle tracks, infarction) was sought. Minimal changes were seen in eight tumours. Tumour growth features (bosselations, enveloping) were present in 57% and 33%, respectively, also microinvasion (42%) and tumour 'buds' (12%). Parotid lesions possessed thicker capsules than submandibular tumours. There was little correlation between capsular thickness and cellular structure. The significant exception was large (> 25 mm) hypocellular parotid tumours which had thinner capsules and could be vulnerable to operative rupture. In 110 standard operations (parotidectomy, submandibular gland excision), capsular exposure was evident in 81%. Field irrigation is recommended to lessen the risk of tumour seeding. This study reaffirms many elements of capsular weakness and suggests that parotidectomy is the operation of choice." @default.
- W2074363716 created "2016-06-24" @default.
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- W2074363716 date "2001-04-01" @default.
- W2074363716 modified "2023-09-27" @default.
- W2074363716 title "Pleomorphic adenomas of the major salivary glands: a study of the capsular form in relation to surgical management" @default.
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- W2074363716 doi "https://doi.org/10.1046/j.1365-2273.2001.00440.x" @default.
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