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• W2074367031 abstract "The European Consortium “High-throughput analysis of single nucleotide polymorphisms for the forensic identification of persons – SNPforID”, has performed a selection of candidate Y-chromosome single nucleotide polymorphisms (SNPs) for making inferences on the geographic origin of an unknown sample. From more than 200 SNPs compiled in the phylogenetic tree published by the Y-Chromosome Consortium, and looking at the population studies previously published, a package of 29 SNPs has been selected for the identification of major population haplogroups. A “Major Y-chromosome haplogroup typing kit” has been developed, which allows the multiplex amplification of all 29 SNPs in a single reaction. Allele genotyping was performed with a single base extension reaction (minisequencing) detected by CE. The validation of the multiplex was performed in a total of 1126 unrelated males distributed among 12 worldwide populations. The approach takes advantage of the specific geographic distribution of the Y-chromosome haplogroups and demonstrates the utility of binary polymorphisms to infer the origin of a male lineage." @default.
• W2074367031 created "2016-06-24" @default.
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• W2074367031 date "2005-12-01" @default.
• W2074367031 modified "2023-10-17" @default.
• W2074367031 title "Introduction of an single nucleodite polymorphism-based “Major Y-chromosome haplogroup typing kit” suitable for predicting the geographical origin of male lineages" @default.
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• W2074367031 doi "https://doi.org/10.1002/elps.200500293" @default.
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