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• W2074383803 abstract "Mycobacterium tuberculosis remains a widespread and devastating human pathogen. Presented here is the characterization of an atypical class I diterpene cyclase from M. tuberculosis that catalyzes an unusual cyclization reaction in converting the known M. tuberculosis metabolite halimadienyl diphosphate to a further cyclized novel diterpene, which we have termed edaxadiene, as it directly inhibits maturation of the phagosomal compartment in which the bacterium is taken up during infection." @default.
• W2074383803 created "2016-06-24" @default.
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• W2074383803 date "2009-07-07" @default.
• W2074383803 modified "2023-10-13" @default.
• W2074383803 title "Edaxadiene: A New Bioactive Diterpene from <i>Mycobacterium tuberculosis</i>" @default.
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• W2074383803 doi "https://doi.org/10.1021/ja9019287" @default.
• W2074383803 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3048449" @default.
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