Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074395703> ?p ?o ?g. }
- W2074395703 endingPage "1173" @default.
- W2074395703 startingPage "1162" @default.
- W2074395703 abstract "Class Cubozoa includes several species of box jellyfish that are harmful to humans. The venoms of box jellyfish are stored and discharged by nematocysts and contain a variety of bioactive proteins that are cytolytic, cytotoxic, inflammatory or lethal. Although cubozoan venoms generally share similar biological activities, the diverse range and severity of effects caused by different species indicate that their venoms vary in protein composition, activity and potency. To date, few individual venom proteins have been thoroughly characterised, however, accumulating evidence suggests that cubozoan jellyfish produce at least one group of homologous bioactive proteins that are labile, basic, haemolytic and similar in molecular mass (42-46 kDa). The novel box jellyfish toxins are also potentially lethal and the cause of cutaneous pain, inflammation and necrosis, similar to that observed in envenomed humans. Secondary structure analysis and remote protein homology predictions suggest that the box jellyfish toxins may act as alpha-pore-forming toxins. However, more research is required to elucidate their structures and investigate their mechanism(s) of action. The biological, biochemical and molecular characteristics of cubozoan venoms and their bioactive protein components are reviewed, with particular focus on cubozoan cytolysins and the newly emerging family of box jellyfish toxins." @default.
- W2074395703 created "2016-06-24" @default.
- W2074395703 creator A5036626579 @default.
- W2074395703 creator A5037945943 @default.
- W2074395703 date "2009-12-01" @default.
- W2074395703 modified "2023-10-07" @default.
- W2074395703 title "Biochemical and molecular characterisation of cubozoan protein toxins" @default.
- W2074395703 cites W122380604 @default.
- W2074395703 cites W1247680957 @default.
- W2074395703 cites W1502565034 @default.
- W2074395703 cites W1589105186 @default.
- W2074395703 cites W1871816128 @default.
- W2074395703 cites W1963743617 @default.
- W2074395703 cites W1967024987 @default.
- W2074395703 cites W1968160465 @default.
- W2074395703 cites W1969919083 @default.
- W2074395703 cites W1976599042 @default.
- W2074395703 cites W1977262821 @default.
- W2074395703 cites W1978267093 @default.
- W2074395703 cites W1979235435 @default.
- W2074395703 cites W1982748780 @default.
- W2074395703 cites W1985609831 @default.
- W2074395703 cites W1989649858 @default.
- W2074395703 cites W1989983958 @default.
- W2074395703 cites W1992462976 @default.
- W2074395703 cites W1997481592 @default.
- W2074395703 cites W1998656860 @default.
- W2074395703 cites W1998866217 @default.
- W2074395703 cites W2001348636 @default.
- W2074395703 cites W2002134413 @default.
- W2074395703 cites W2007448113 @default.
- W2074395703 cites W2011851516 @default.
- W2074395703 cites W2012444828 @default.
- W2074395703 cites W2015936607 @default.
- W2074395703 cites W2016777872 @default.
- W2074395703 cites W2017208796 @default.
- W2074395703 cites W2018187695 @default.
- W2074395703 cites W2018532807 @default.
- W2074395703 cites W2020652389 @default.
- W2074395703 cites W2020869590 @default.
- W2074395703 cites W2021561156 @default.
- W2074395703 cites W2025117402 @default.
- W2074395703 cites W2025239874 @default.
- W2074395703 cites W2026132923 @default.
- W2074395703 cites W2027734977 @default.
- W2074395703 cites W2028114796 @default.
- W2074395703 cites W2029683085 @default.
- W2074395703 cites W2030174975 @default.
- W2074395703 cites W2030424226 @default.
- W2074395703 cites W2038412949 @default.
- W2074395703 cites W2040577840 @default.
- W2074395703 cites W2041322125 @default.
- W2074395703 cites W2041360751 @default.
- W2074395703 cites W2041402342 @default.
- W2074395703 cites W2042363666 @default.
- W2074395703 cites W204331914 @default.
- W2074395703 cites W2044145349 @default.
- W2074395703 cites W2044516757 @default.
- W2074395703 cites W2047141903 @default.
- W2074395703 cites W2047679232 @default.
- W2074395703 cites W2048354268 @default.
- W2074395703 cites W2051808439 @default.
- W2074395703 cites W2053322328 @default.
- W2074395703 cites W2053778162 @default.
- W2074395703 cites W2054636364 @default.
- W2074395703 cites W2056804261 @default.
- W2074395703 cites W2058921900 @default.
- W2074395703 cites W2061803135 @default.
- W2074395703 cites W2065741587 @default.
- W2074395703 cites W2068951358 @default.
- W2074395703 cites W2073013257 @default.
- W2074395703 cites W2073781651 @default.
- W2074395703 cites W2076222762 @default.
- W2074395703 cites W2080866727 @default.
- W2074395703 cites W2081506967 @default.
- W2074395703 cites W2082522575 @default.
- W2074395703 cites W2082632721 @default.
- W2074395703 cites W2082667898 @default.
- W2074395703 cites W2087239636 @default.
- W2074395703 cites W2089084432 @default.
- W2074395703 cites W2090712498 @default.
- W2074395703 cites W2092365849 @default.
- W2074395703 cites W2092726093 @default.
- W2074395703 cites W2106882534 @default.
- W2074395703 cites W2109994379 @default.
- W2074395703 cites W2110193388 @default.
- W2074395703 cites W2113977017 @default.
- W2074395703 cites W2123707870 @default.
- W2074395703 cites W2125843194 @default.
- W2074395703 cites W2137695709 @default.
- W2074395703 cites W2140876175 @default.
- W2074395703 cites W2151552904 @default.
- W2074395703 cites W2151559478 @default.
- W2074395703 cites W2154898118 @default.
- W2074395703 cites W2158356919 @default.
- W2074395703 cites W2161210482 @default.
- W2074395703 cites W2166148586 @default.
- W2074395703 cites W2167943820 @default.