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- W2074401693 abstract "No AccessJournal of UrologyClinical Urology: Original Articles1 May 1998NEPHRON SPARING SURGERY FOR RENAL CELL CARCINOMA 4 CM. OR LESS IN DIAMETER: INDICATED OR UNDER TREATED? H. WUNDERLICH, O. REICHELT, S. SCHUMANN, A. SCHLICHTER, H. KOSMEHL, W. WERNER, R. VOLLANDT, and J. SCHUBERT H. WUNDERLICHH. WUNDERLICH More articles by this author , O. REICHELTO. REICHELT More articles by this author , S. SCHUMANNS. SCHUMANN More articles by this author , A. SCHLICHTERA. SCHLICHTER More articles by this author , H. KOSMEHLH. KOSMEHL More articles by this author , W. WERNERW. WERNER More articles by this author , R. VOLLANDTR. VOLLANDT More articles by this author , and J. SCHUBERTJ. SCHUBERT More articles by this author View All Author Informationhttps://doi.org/10.1097/00005392-199805000-00012AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Although radical nephrectomy is the standard treatment for localized unilateral renal cell carcinoma with a normal contralateral kidney, there is ongoing interest in the use of nephron sparing surgery or partial nephrectomy in such cases. The extent of radical surgery in such cases has also been reconsidered in view of the uncertainty regarding the malignant of benign nature. Materials and Methods: Of 14,793 autopsies in Jena from 1985 until 1995 there were 260 renal cell carcinomas. Of the 260 renal cell carcinomas the diameter was 40 mm. or less in 104. These 104 tumors were divided into group 1-20 mm. or less (33 cases), group 2-21 to 30 mm. (28) and group 3-31 to 40 mm. (43). Results: Grade 1 renal cell carcinomas decreased in frequency with increasing tumor diameter, while an opposite result was noted for grade 3. Lymph node and distant metastases were well correlated with tumor size. With an increase in tumor size the frequency of venous involvement increased as well. Significantly more multifocal malignant renal cell carcinomas were seen in tumors between 21 and 40 mm. compared to those 20 mm. or less in diameter. Conclusions: The metastatic potential and biology of these small nodules are not yet known. To lower the risk of local recurrence the results of our study suggest that nephron sparing surgery might be advisable in patients with renal cell carcinoma 20 mm. or less in diameter. References 1 : Small renal-cell carcinomas: clinical and imaging features. Urol. Int.1993; 51: 19. Google Scholar 2 : Nephron-sparing surgery for renal cell carcinoma. J. Urol.1993; 144: 1. Google Scholar 3 : Clinicopathological characteristics of small renal cell carcinoma. Int. Urol. Nephrol.1994; 26: 621. Google Scholar 4 : Clinical analysis of incidentally found renal cell carcinoma. Eur. Urol.1991; 19: 109. Google Scholar 5 : Small renal cell carcinoma: resolving a diagnostic dilemma. Radiology1988; 160: 637. Google Scholar 6 : Computed tomography of renal oncocytoma. J. Comput. Assist. Tomogr.1984; 8: 284. Google Scholar 7 : Disease of the kidney. In: Urologic Pathology. Edited by . Philadelphia: W. B. Saunders Co.1989: 423. chapt. 8. Google Scholar 8 : Clinical implication of pathologic subtypes in renal cell carcinoma. Sem. Urol.1990; 125: 31. Google Scholar 9 : Histologic assessment and clinical prognosis of renal adenoma. J. Urol.1970; 103: 31. Link, Google Scholar 10 : Tumors and tumor-like lesions of the kidney. Curr. Probl. Cancer1986; 10: 53. Google Scholar 11 : Small renal neoplasms: diagnostic imaging, pathologic features, and clinical course. Radiology1986; 158: 113. Google Scholar 12 : Improvement in survival of patients with renal cell carcinoma-the role of the serendipitously detected tumor. J. Urol.1988; 140: 487. Link, Google Scholar 13 : Renal diseases. Philadelphia: Lea & Febiger1950. Chapt. 435. Google Scholar 14 : Renal cell carcinoma at autopsy. J. Urol.1967; 97: 978. Link, Google Scholar 15 : Small renal adenocarcinoma with metastases. J. Urol.1980; 124: 132. Link, Google Scholar From the Department of Urology, Institute of Pathology and Institute of Medical Statistics, Friedrich-Schiller-University, Jena, Germany.© 1998 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byKume H, Suzuki M, Fujimura T, Fukuhara H, Enomoto Y, Nishimatsu H and Homma Y (2018) Distant Metastasis of Renal Cell Carcinoma With a Diameter of 3 cm or Less—Which is Aggressive Cancer?Journal of Urology, VOL. 184, NO. 1, (64-68), Online publication date: 1-Jul-2010.Thompson R, Hill J, Babayev Y, Cronin A, Kaag M, Kundu S, Bernstein M, Coleman J, Dalbagni G, Touijer K and Russo P (2018) Metastatic Renal Cell Carcinoma Risk According to Tumor SizeJournal of Urology, VOL. 182, NO. 1, (41-45), Online publication date: 1-Jul-2009.Kunkle D, Crispen P, Li T and Uzzo R (2018) Tumor Size Predicts Synchronous Metastatic Renal Cell Carcinoma: Implications for Surveillance of Small Renal MassesJournal of Urology, VOL. 177, NO. 5, (1692-1697), Online publication date: 1-May-2007.DRACHENBERG D, MENA O, CHOYKE P, LINEHAN W and WALTHER M (2018) PARENCHYMAL SPARING SURGERY FOR CENTRAL RENAL TUMORS IN PATIENTS WITH HEREDITARY RENAL CANCERSJournal of Urology, VOL. 172, NO. 1, (49-53), Online publication date: 1-Jul-2004.CHAN D, CADEDDU J, JARRETT T, MARSHALL F and KAVOUSSI L (2018) LAPAROSCOPIC RADICAL NEPHRECTOMY: CANCER CONTROL FOR RENAL CELL CARCINOMAJournal of Urology, VOL. 166, NO. 6, (2095-2100), Online publication date: 1-Dec-2001.UZZO R and NOVICK A (2018) NEPHRON SPARING SURGERY FOR RENAL TUMORS: INDICATIONS, TECHNIQUES AND OUTCOMESJournal of Urology, VOL. 166, NO. 1, (6-18), Online publication date: 1-Jul-2001.BALTACI S, ORHAN D, SOYUPEK S, BEDÜK Y, TULUNAY Ö and GÖĞÜŞ O (2018) INFLUENCE OF TUMOR STAGE, SIZE, GRADE, VASCULAR INVOLVEMENT, HISTOLOGICAL CELL TYPE AND HISTOLOGICAL PATTERN ON MULTIFOCALITY OF RENAL CELL CARCINOMAJournal of Urology, VOL. 164, NO. 1, (36-39), Online publication date: 1-Jul-2000.BLACK P, FILIPAS D, FICHTNER J, HOHENFELLNER R and THÜROFF J (2018) NEPHRON SPARING SURGERY FOR CENTRAL RENAL TUMORS: EXPERIENCE WITH 33 CASESJournal of Urology, VOL. 163, NO. 3, (737-743), Online publication date: 1-Mar-2000. Volume 159Issue 5May 1998Page: 1465-1469 Advertisement Copyright & Permissions© 1998 by American Urological Association, Inc.MetricsAuthor Information H. WUNDERLICH More articles by this author O. REICHELT More articles by this author S. SCHUMANN More articles by this author A. SCHLICHTER More articles by this author H. KOSMEHL More articles by this author W. WERNER More articles by this author R. VOLLANDT More articles by this author J. SCHUBERT More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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