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- W2074408092 abstract "Objective: To clarify the structural features of conjunctivochalasis histopathologically. Methods: A biopsy of redundant conjunctiva from the same anatomic location of 44 eyes with conjunctivochalasis was examined histologically. All patients, 9 men and 35 women, aged 66.6 ± 7.5 years (mean ± SD, 50.87 years), underwent conjunctivoplasty (termed tear meniscus reconstruction). Results: In all 44 cases, histologic examination disclosed normal conjunctival epithelium and negligible inflammation and lymphocyte infiltration; 39 patients manifested microscopic lymphangiectasia. Elastica van Gieson staining demonstrated elastic fiber fragmentation and sparsely assembled collagen fibers in all 44 cases. There was no discernible difference between specimens from patients with and without complications including tear-deficient dry eye, meibomian gland dysfunction, and clinically observable lymphangiectasia and/or pinguecula. Conclusion: Based on our histopathologic findings, we hypothesize that mechanical forces between the lower lid and conjunctiva gradually interfered with lymphatic flow. Chronic, prolonged mechanical obstruction of lymphatic flow may result in lymphatic dilation and eventually give rise to clinical conjunctivochalasis." @default.
- W2074408092 created "2016-06-24" @default.
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- W2074408092 date "2004-04-01" @default.
- W2074408092 modified "2023-10-17" @default.
- W2074408092 title "Clinicopathologic Study of Conjunctivochalasis" @default.
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- W2074408092 doi "https://doi.org/10.1097/00003226-200404000-00013" @default.
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