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• W2074414263 abstract "Conocer el grado de control del colesterol de las lipoproteínas de baja densidad (cLDL) en pacientes con enfermedad renal crónica (ERC), su tratamiento farmacológico y el porcentaje de reducción necesario para alcanzar objetivos según las nuevas guías europeas para el manejo de la dislipidemia. Estudio descriptivo transversal entre los pacientes atendidos en atención primaria con ERC (FG < 60 ml/min/1,73 m2) entre 18 y 85 años. Se registraron edad, sexo, factores de riesgo, enfermedades cardiovasculares asociadas, presión arterial, glucosa, creatinina, filtrado glomerular estimado (FGE), colesterol total, triglicéridos, colesterol de las lipoproteínas de alta densidad (cHDL) y cLDL. Se consideró control lipídico un valor < 70 mg/dl de cLDL. Se registró el tipo de fármaco y dosis, así como el porcentaje necesario de reducción para alcanzar objetivos. Encontramos 384 pacientes con ERC, de los cuales la mayoría (92,4%) corresponden al estadio 3, con una media de edad de 75 años (62% mujeres). El 76,8% presentaban dislipidemia. El 10,7% de todos los pacientes alcanzaban el objetivo de cLDL < 70 mg/dl, mientras que entre los que recibían tratamiento farmacológico el control se lograba en el 16%. La mitad de los pacientes estaban tomando estatinas y un 5%, fibratos. De los tratados, el 45% estaban con dosis intermedias de estatinas, el 38% con dosis altas y, de estos, el 69% precisaban más de un 25% adicional de reducción de cLDL para alcanzar el objetivo. Se ha observado un escaso grado de control lipídico en la población estudiada, incluso en los tratados con dosis altas de estatinas. To find out the grade of control of LDL cholesterol in patients with chronic kidney disease (CKD), their pharmacological treatment and the percentage of lowering needed to reach objectives according to the new European Guidelines of treatment of dyslipidemia. It was made a cross-sectional descriptive study among patients with CKD attended in primary health care (GFR <60 ml/min/1,73 m2) between the age of 18 and 85 years old. Age, sex, risk factors and cardiovascular disease presence, blood pressure, glucose, creatinine, estimated glomerular filtration (EGFR), total cholesterol, triglycerides, HDL cholesterol and LDL cholesterol were registered. Numbers of 70 mg/dL in LDL were considered as right lipid control. Type and doses of drug were registered too, as well as the reduction needed percentage to attain objectives. We found out 384 patients with CKD, most of them (92,4%) corresponding to 3rd stage, with a medium age of 75 years old (62% female). Dislypidemia was found in 76.8%. LDL < 70 mg/dL objective was attained by 10.7% of all patients, meanwhile control was reached by a 16% among the ones receiving pharmacological treatment. Half of patients were taking statins and a 5% were taking fibrates. Among the treated ones, 45% were treated with intermediate doses of statins and the 38% were treated with high ones. From that last ones, 69% needed more than a 25% of additional reduction of LDL cholesterol to attain the objective. A low grade of lipid control was found in the studied population, even in the ones treated with high doses of statins." @default.
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• W2074414263 date "2012-11-01" @default.
• W2074414263 modified "2023-09-27" @default.
• W2074414263 title "Colesterol de las lipoproteínas de baja densidad <70mg/dl en la enfermedad renal crónica. ¿Ficción o realidad?" @default.
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• W2074414263 doi "https://doi.org/10.1016/j.arteri.2012.09.006" @default.
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