FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074420105> ?p ?o ?g. }

• W2074420105 endingPage "9983" @default.
• W2074420105 startingPage "9975" @default.
• W2074420105 abstract "High-density lipoprotein (HDL) is a natural nanoparticle that transports peripheral cholesterol to the liver. Reconstituted high-density lipoprotein (rHDL) exhibits antiatherothrombotic properties and is being considered as a natural treatment for cardiovascular diseases. Furthermore, HDL nanoparticle platforms have been created for targeted delivery of therapeutic and diagnostic agents. The current methods for HDL reconstitution involve lengthy procedures that are challenging to scale up. A central need in the synthesis of rHDL, and multifunctional nanomaterials in general, is to establish large-scale production of reproducible and homogeneous batches in a simple and efficient fashion. Here, we present a large-scale microfluidics-based manufacturing method for single-step synthesis of HDL-mimicking nanomaterials (μHDL). μHDL is shown to have the same properties (e.g., size, morphology, bioactivity) as conventionally reconstituted HDL and native HDL. In addition, we were able to incorporate simvastatin (a hydrophobic drug) into μHDL, as well as gold, iron oxide, quantum dot nanocrystals or fluorophores to enable its detection by computed tomography (CT), magnetic resonance imaging (MRI), or fluorescence microscopy, respectively. Our approach may contribute to effective development and optimization of lipoprotein-based nanomaterials for medical imaging and drug delivery." @default.
• W2074420105 created "2016-06-24" @default.
• W2074420105 creator A5004502841 @default.
• W2074420105 creator A5010297916 @default.
• W2074420105 creator A5035258831 @default.
• W2074420105 creator A5042597057 @default.
• W2074420105 creator A5045955281 @default.
• W2074420105 creator A5053775273 @default.
• W2074420105 creator A5055829543 @default.
• W2074420105 creator A5063601436 @default.
• W2074420105 creator A5069031998 @default.
• W2074420105 creator A5069869461 @default.
• W2074420105 creator A5070825558 @default.
• W2074420105 creator A5088448170 @default.
• W2074420105 creator A5089434484 @default.
• W2074420105 date "2013-10-03" @default.
• W2074420105 modified "2023-10-03" @default.
• W2074420105 title "Single Step Reconstitution of Multifunctional High-Density Lipoprotein-Derived Nanomaterials Using Microfluidics" @default.
• W2074420105 cites W1029596508 @default.
• W2074420105 cites W1565394441 @default.
• W2074420105 cites W1978057376 @default.
• W2074420105 cites W1979080082 @default.
• W2074420105 cites W1985170971 @default.
• W2074420105 cites W1998993589 @default.
• W2074420105 cites W2002409002 @default.
• W2074420105 cites W2002862770 @default.
• W2074420105 cites W2003523198 @default.
• W2074420105 cites W2005082260 @default.
• W2074420105 cites W2020438216 @default.
• W2074420105 cites W2024664318 @default.
• W2074420105 cites W2037678728 @default.
• W2074420105 cites W2039422687 @default.
• W2074420105 cites W2039685011 @default.
• W2074420105 cites W2044598213 @default.
• W2074420105 cites W2051434186 @default.
• W2074420105 cites W2061612552 @default.
• W2074420105 cites W2062182733 @default.
• W2074420105 cites W2076021360 @default.
• W2074420105 cites W2080566499 @default.
• W2074420105 cites W2085194018 @default.
• W2074420105 cites W2089677494 @default.
• W2074420105 cites W2090174920 @default.
• W2074420105 cites W2095507444 @default.
• W2074420105 cites W2104792407 @default.
• W2074420105 cites W2105050495 @default.
• W2074420105 cites W2108297214 @default.
• W2074420105 cites W2110960044 @default.
• W2074420105 cites W2115255784 @default.
• W2074420105 cites W2116986583 @default.
• W2074420105 cites W2120764900 @default.
• W2074420105 cites W2122216727 @default.
• W2074420105 cites W2122963423 @default.
• W2074420105 cites W2131620609 @default.
• W2074420105 cites W2135503869 @default.
• W2074420105 cites W2159087408 @default.
• W2074420105 cites W2162994503 @default.
• W2074420105 cites W2163095440 @default.
• W2074420105 cites W2165555463 @default.
• W2074420105 cites W2166734878 @default.
• W2074420105 cites W2339616051 @default.
• W2074420105 cites W2442172771 @default.
• W2074420105 cites W4235732579 @default.
• W2074420105 cites W4256475235 @default.
• W2074420105 doi "https://doi.org/10.1021/nn4039063" @default.
• W2074420105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4104519" @default.
• W2074420105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24079940" @default.
• W2074420105 hasPublicationYear "2013" @default.
• W2074420105 type Work @default.
• W2074420105 sameAs 2074420105 @default.
• W2074420105 citedByCount "99" @default.
• W2074420105 countsByYear W20744201052014 @default.
• W2074420105 countsByYear W20744201052015 @default.
• W2074420105 countsByYear W20744201052016 @default.
• W2074420105 countsByYear W20744201052017 @default.
• W2074420105 countsByYear W20744201052018 @default.
• W2074420105 countsByYear W20744201052019 @default.
• W2074420105 countsByYear W20744201052020 @default.
• W2074420105 countsByYear W20744201052021 @default.
• W2074420105 countsByYear W20744201052022 @default.
• W2074420105 countsByYear W20744201052023 @default.
• W2074420105 crossrefType "journal-article" @default.
• W2074420105 hasAuthorship W2074420105A5004502841 @default.
• W2074420105 hasAuthorship W2074420105A5010297916 @default.
• W2074420105 hasAuthorship W2074420105A5035258831 @default.
• W2074420105 hasAuthorship W2074420105A5042597057 @default.
• W2074420105 hasAuthorship W2074420105A5045955281 @default.
• W2074420105 hasAuthorship W2074420105A5053775273 @default.
• W2074420105 hasAuthorship W2074420105A5055829543 @default.
• W2074420105 hasAuthorship W2074420105A5063601436 @default.
• W2074420105 hasAuthorship W2074420105A5069031998 @default.
• W2074420105 hasAuthorship W2074420105A5069869461 @default.
• W2074420105 hasAuthorship W2074420105A5070825558 @default.
• W2074420105 hasAuthorship W2074420105A5088448170 @default.
• W2074420105 hasAuthorship W2074420105A5089434484 @default.
• W2074420105 hasBestOaLocation W20744201052 @default.
• W2074420105 hasConcept C138631740 @default.
• W2074420105 hasConcept C155672457 @default.
• W2074420105 hasConcept C171250308 @default.

• next