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• W2074421871 startingPage "1693" @default.
• W2074421871 abstract "OBJECTIVES: Severe transient hypothyroxinemia in premature infants is associated with cerebral palsy and mental retardation: this study assessed its prevalence in very premature infants. METHODS: Congenital hypothyroidism screening programs in three states provided thyroxine values for 919 newborn infants younger than 29 weeks who were enrolled in a multicenter study. RESULTS: Thyroxine values were lower than 4.0 micrograms/dL in 21% of survivors and increased each week by 0.6 microgram/dL (95% confidence interval [CI] = 0.4, 0.7). At tests done 1 to 2 days after birth, levels were 2.5 micrograms/dL higher (95% CI = 1.8, 3.3) than at tests done at 8 to 14 days. In New York, levels were 1.0 microgram/dL higher (95% CI = 0.3, 1.6) than elsewhere. The levels of infants who died were 1.3 micrograms/dL lower (95% CI = 0.6, 2.0) than those of survivors. CONCLUSIONS: Severe transient hypothyroxinemia is common in very premature infants and deserves further study." @default.
• W2074421871 created "2016-06-24" @default.
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• W2074421871 date "1997-10-01" @default.
• W2074421871 modified "2023-09-25" @default.
• W2074421871 title "Thyroxine values from newborn screening of 919 infants born before 29 weeks' gestation." @default.
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• W2074421871 doi "https://doi.org/10.2105/ajph.87.10.1693" @default.
• W2074421871 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1381138" @default.
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