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• W2074422606 abstract "Retinotopic map development in nonmammalian vertebrates appears to be controlled by molecules that guide or restrict retinal axons to correct locations in their targets. However, the retinotopic map in the superior colliculus (SC) of the rat is developed instead by a topographic bias in collateral branching and arborization. Temporal retinal axons extending across alternating membranes from the topographically correct rostral SC or the incorrect caudal SC of embryonic rats preferentially branch on rostral membranes. Branching preference is due to an inhibitory phosphatidylinositol-linked molecule in the caudal SC. Thus, position-encoding membrane-bound molecules may establish retinotopic maps in mammals by regulating axon branching, not by directing axon growth." @default.
• W2074422606 created "2016-06-24" @default.
• W2074422606 creator A5012926933 @default.
• W2074422606 creator A5059737501 @default.
• W2074422606 date "1994-08-05" @default.
• W2074422606 modified "2023-10-18" @default.
• W2074422606 title "Control of Topographic Retinal Axon Branching by Inhibitory Membrane-Bound Molecules" @default.
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• W2074422606 doi "https://doi.org/10.1126/science.8047886" @default.
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