Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074482627> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2074482627 endingPage "95" @default.
- W2074482627 startingPage "91" @default.
- W2074482627 abstract "The reproductive system effects of cocaine were studied in male rats. The analysis included measurements of circulating levels of luteinizing hormone (LH) and testosterone (T) by radioimmunoassay (RIA). The weights of the testes and sex accessory organs were also assessed and compared with control animals. Dosage level, duration of treatment, and interval between injection and sacrifice were the parameters examined. Following a single intraperitoneal (IP) injection, LH levels decreased over a 3-hour period. At a high dosage (40 mg/kg), cocaine caused a significant elevation in serum T followed by a significant depression of T for at least 2 hours. When administered chronically for 15 days, the low dose group (10 mg/kg) did not vary significantly from the vehicle controls. However, the high dose group had lower LH and T levels, as well as correspondingly lighter weight seminal vesicles and epididymis. No changes were noted in the weights of the ventral prostate or testes. This research suggests that cocaine acts primarily at the hypothalamic-hypophyseal axis with a possible secondary action at the gonadal level." @default.
- W2074482627 created "2016-06-24" @default.
- W2074482627 creator A5033140862 @default.
- W2074482627 creator A5067703165 @default.
- W2074482627 date "1989-01-01" @default.
- W2074482627 modified "2023-09-27" @default.
- W2074482627 title "Effects of cocaine hydrochloride on the male reproductive system" @default.
- W2074482627 cites W1986477161 @default.
- W2074482627 cites W2066830836 @default.
- W2074482627 cites W2070926198 @default.
- W2074482627 cites W2396262542 @default.
- W2074482627 cites W4245425254 @default.
- W2074482627 cites W4253082908 @default.
- W2074482627 doi "https://doi.org/10.1016/0024-3205(89)90440-2" @default.
- W2074482627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2747420" @default.
- W2074482627 hasPublicationYear "1989" @default.
- W2074482627 type Work @default.
- W2074482627 sameAs 2074482627 @default.
- W2074482627 citedByCount "27" @default.
- W2074482627 countsByYear W20744826272017 @default.
- W2074482627 countsByYear W20744826272019 @default.
- W2074482627 countsByYear W20744826272022 @default.
- W2074482627 countsByYear W20744826272023 @default.
- W2074482627 crossrefType "journal-article" @default.
- W2074482627 hasAuthorship W2074482627A5033140862 @default.
- W2074482627 hasAuthorship W2074482627A5067703165 @default.
- W2074482627 hasConcept C121608353 @default.
- W2074482627 hasConcept C126322002 @default.
- W2074482627 hasConcept C134018914 @default.
- W2074482627 hasConcept C16685009 @default.
- W2074482627 hasConcept C176685330 @default.
- W2074482627 hasConcept C2776235491 @default.
- W2074482627 hasConcept C2778575703 @default.
- W2074482627 hasConcept C2779279991 @default.
- W2074482627 hasConcept C2781087480 @default.
- W2074482627 hasConcept C2781171107 @default.
- W2074482627 hasConcept C2781254305 @default.
- W2074482627 hasConcept C71315377 @default.
- W2074482627 hasConcept C71924100 @default.
- W2074482627 hasConcept C86803240 @default.
- W2074482627 hasConceptScore W2074482627C121608353 @default.
- W2074482627 hasConceptScore W2074482627C126322002 @default.
- W2074482627 hasConceptScore W2074482627C134018914 @default.
- W2074482627 hasConceptScore W2074482627C16685009 @default.
- W2074482627 hasConceptScore W2074482627C176685330 @default.
- W2074482627 hasConceptScore W2074482627C2776235491 @default.
- W2074482627 hasConceptScore W2074482627C2778575703 @default.
- W2074482627 hasConceptScore W2074482627C2779279991 @default.
- W2074482627 hasConceptScore W2074482627C2781087480 @default.
- W2074482627 hasConceptScore W2074482627C2781171107 @default.
- W2074482627 hasConceptScore W2074482627C2781254305 @default.
- W2074482627 hasConceptScore W2074482627C71315377 @default.
- W2074482627 hasConceptScore W2074482627C71924100 @default.
- W2074482627 hasConceptScore W2074482627C86803240 @default.
- W2074482627 hasIssue "1" @default.
- W2074482627 hasLocation W20744826271 @default.
- W2074482627 hasLocation W20744826272 @default.
- W2074482627 hasOpenAccess W2074482627 @default.
- W2074482627 hasPrimaryLocation W20744826271 @default.
- W2074482627 hasRelatedWork W1988486434 @default.
- W2074482627 hasRelatedWork W1999611386 @default.
- W2074482627 hasRelatedWork W1999831221 @default.
- W2074482627 hasRelatedWork W2012502375 @default.
- W2074482627 hasRelatedWork W2047880909 @default.
- W2074482627 hasRelatedWork W2064034534 @default.
- W2074482627 hasRelatedWork W2073502422 @default.
- W2074482627 hasRelatedWork W2159598174 @default.
- W2074482627 hasRelatedWork W2163989763 @default.
- W2074482627 hasRelatedWork W2313856518 @default.
- W2074482627 hasVolume "45" @default.
- W2074482627 isParatext "false" @default.
- W2074482627 isRetracted "false" @default.
- W2074482627 magId "2074482627" @default.
- W2074482627 workType "article" @default.