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- W20744906 abstract "Background/Objective: Hepatitis B virus (HBV) infection has remained a global public health challenge. Nigeria is in the high endemicitygroup with a prevalence of 8% or higher. The authors seized the opportunity of the 2010. World Hepatitis Day to mount a public enlightenmentcampaign and also screen civil servant in Enugu State of Nigeria for the infection.Materials and methods: In this cross-sectional study, civil servants attached to Government House, Enugu, Nigeria, were administered astructured questionnaire containing the putative risk factors for HBV transmission. They also underwent screening for hepatitis B surfaceantigen (HBsAg) in blood.Results: Out of 395 civil servants (206 males and 189 females) who participated in the screening, 36 were position for HBsAg giving aseroprevalence of 7.6%. Majority of the seropostive subjects (86.7%) were females (p < 0. 001).Among the risk factors examined, past history of native uvulectomy, sharing of toothbrush, sharing of razor blades and hair clippers weresignificantly more prevalent in the HBsAg positive group compared to the HBsAg negative subjects.In the females who had circumcision, the HBsAg seroprevalence was significantly higher than in the uncircumcized group (p = 0.014, oddsratio = 3.13).Conclusion: The seroprevalence of HBsAg in civil servants of Enugu State of Nigeria was 7.6%. More females than males were HBsAgseropositive and this may be related to previous circumcision in the females.Abbreviations: HBV�Hepatitis B virus; Apo�Apolipoprotein; Tg�Transgenic; HBsAg�Hepatitis B surface antigen; HCV�Hepatitis Cvirus; WHO�World Health Organization." @default.
- W20744906 created "2016-06-24" @default.
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- W20744906 date "2010-09-01" @default.
- W20744906 modified "2023-10-01" @default.
- W20744906 title "Relatively High Seroprevalence of Hepatitis B Surface Antigen in Female Civil Servants in Enugu State of Nigeria" @default.
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- W20744906 doi "https://doi.org/10.5005/jp-journals-10018-1004" @default.
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