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- W2074491787 abstract "Loxoprofen racemate를 분리하기 위해 SMB에서 운전조건을 탐색하였다. Aspen simulator를 이용하여 전산모사를 함으로써 loxoprofen racemate를 분리할 수 있는 운전조건을 다음과 같이 제시할 수 있었다. Raffinate 순도를 증가시키기 위해 삼각도에서 왼쪽 중간 부분의 <TEX>$m_2$</TEX>, <TEX>$m_3$</TEX> 좌표를 정하여야 하며 내부농도 분포도에서 raffinate와 extract 분포곡선을 겹치지 않도록 하여야 한다. Simulated moving bed(SMB) chromatography was simulated for separating loxoprofen racemates. Aspen chromatography simulator was utilized with Henry's constants of loxoprofen racemates which were obtained by batch chromatography experiments. Raffinate stream concentrations as well as purities were calculated with various <TEX>$m_2$</TEX> and <TEX>$m_3$</TEX> values in the triangle diagram obtained from two Henry's constants 7.9 and 10.1. Purity values are high under the conditions that the <TEX>$m_2-m^3$</TEX> coordinates are near the left central region in the diagram and feed flow rates are lower. Concentration profiles of raffinate and extract streams along SMB columns explain the purity change in the case of increasing the column numbers installed at SMB." @default.
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- W2074491787 date "2011-10-01" @default.
- W2074491787 modified "2023-10-02" @default.
- W2074491787 title "Simulated Moving Bed(SMB) Chromatography Simulation for Loxoprofen Racemates Separation" @default.
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- W2074491787 doi "https://doi.org/10.9713/kcer.2011.49.5.623" @default.
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