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• W2074493555 abstract "In this study the modulatory effects of a well-defined surfactant preparation on blood leukocytes were investigated. The expression of the cell surface receptor MAC-1 was analyzed by flow cytofluorometry, and the metabolic response was measured by a chemiluminescence technique. An increase (p less than 0.05) in the MAC-1 receptor expression was observed in the granulocytes but not in the monocytes. There was a decrease in the metabolic response of the leukocytes after stimulation with phorbol myristate acetate (PMA) and a delay (p less than 0.01 for both) in the peak activity. Formyl-methionyl-leucyl-phenylalanine (fMLP) caused an increased peak (p less than 0.01). Thus, the surfactant preparation had a modulatory effect on blood leukocytes with regard to the expression of the cell surface receptor MAC-1 and the metabolic response." @default.
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• W2074493555 date "1992-07-01" @default.
• W2074493555 modified "2023-09-24" @default.
• W2074493555 title "Increased expression of adhesion proteins (MAC-1) and altered metabolic response in human leukocytes exposed to surfactantin vitro" @default.
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• W2074493555 doi "https://doi.org/10.1111/j.1699-0463.1992.tb03986.x" @default.
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