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- W2074501836 abstract "A defensin-like gene, BmdefA, was rediscovered in the silkworm genome and expressed sequence tags databases. The open reading frame of BmdefA encodes a prepropeptide consisting of a 22-residue signal peptide, a 34-residue propeptide, and a 36-residue mature peptide with a molecular mass of 4.0 kDa. The mature peptide possesses the characteristic six-cysteine motif of insect defensins, and its predicted isoelectric point is 4.12, indicating it is a novel anionic defensin. An intron is present in BmdefA and several cis-regulatory elements are in the regulating region. It is transcribed constitutively at a high level in the hemocyte, silk gland, head, and ovary of the silkworm larvae, and in the fat body of early-stage pupae and moth. BmdefA is also strongly induced by immune challenge. These results suggest that BmdefA plays an important role in both immunity and metamorphosis." @default.
- W2074501836 created "2016-06-24" @default.
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- W2074501836 date "2008-03-22" @default.
- W2074501836 modified "2023-10-15" @default.
- W2074501836 title "Sequence structure and expression pattern of a novel anionic defensin-like gene from silkworm (Bombyx mori)" @default.
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- W2074501836 doi "https://doi.org/10.1007/s11033-008-9233-4" @default.
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