Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074505983> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W2074505983 endingPage "549" @default.
- W2074505983 startingPage "533" @default.
- W2074505983 abstract "1. The Na content of rat red cells was found to be 4.40 m-mole/l. cells. When incubated in K(Rb)-free Na this value was doubled in 1 hr, whereas in K(Rb)-free choline it was reduced to about 35% in the same period of time.2. In cells with elevated Na (13.70 m-mole/l.) the activation curve of Rb influx by external Rb reached the same V(max) in sodium as in choline. The shape of the curve was sigmoid in the first case (K(m) about 1.05 mM) and hyperbolic in the second (K(m) about 0.20 mM).3. The activation curve of rubidium influx by internal sodium was linear at least up to 12 m-mole/l. cells with a slope of 0.84. From this concentration it could increase more steeply, though the data is insufficient to assure it.4. In normal cells the efflux of Na in K(Rb)-free Na Ringer was 5.64 m-mole/l. cells. hr, and it was reduced to 4.32 m-mole by 10(-4)M ouabain. This was accompanied by a reduction of Na influx by 4.14 m-mole, representing then a Na-Na ouabain-sensitive exchange mechanism.5. At a concentration of 5 mM, external Rb increased Na efflux in 2.32 m-mole/l. cells. hr above the K(Rb)-free levels, and reduced Na influx by 2.13 m-mole.6. It is proposed that the Na pump is able to operate even in the absence of external K(Rb), though at reduced rate and on a Na-Na exchange basis (Na is the only monovalent cation in the bathing solution). External K(Rb) would have two actions: to increase the rate of shuttling of the carrier (catalytic effect) and to switch the Na-Na to a Na-K(Rb) exchange.7. These results raise a question of the real significance of the Na/K(Rb) ;coupling' ratio and the K-free effect on the Na pump mechanism." @default.
- W2074505983 created "2016-06-24" @default.
- W2074505983 creator A5043561025 @default.
- W2074505983 creator A5044559578 @default.
- W2074505983 date "1971-11-01" @default.
- W2074505983 modified "2023-09-25" @default.
- W2074505983 title "Sodium and rubidium fluxes in rat red blood cells" @default.
- W2074505983 cites W1551234630 @default.
- W2074505983 cites W1968158388 @default.
- W2074505983 cites W1968909528 @default.
- W2074505983 cites W2007656190 @default.
- W2074505983 cites W2009659059 @default.
- W2074505983 cites W2081541395 @default.
- W2074505983 cites W2086273817 @default.
- W2074505983 cites W2109963077 @default.
- W2074505983 cites W2124548433 @default.
- W2074505983 cites W2134456348 @default.
- W2074505983 cites W2153192653 @default.
- W2074505983 cites W2223543523 @default.
- W2074505983 cites W2414499681 @default.
- W2074505983 cites W84372858 @default.
- W2074505983 doi "https://doi.org/10.1113/jphysiol.1971.sp009632" @default.
- W2074505983 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1331600" @default.
- W2074505983 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5133948" @default.
- W2074505983 hasPublicationYear "1971" @default.
- W2074505983 type Work @default.
- W2074505983 sameAs 2074505983 @default.
- W2074505983 citedByCount "29" @default.
- W2074505983 crossrefType "journal-article" @default.
- W2074505983 hasAuthorship W2074505983A5043561025 @default.
- W2074505983 hasAuthorship W2074505983A5044559578 @default.
- W2074505983 hasBestOaLocation W20745059832 @default.
- W2074505983 hasConcept C113196181 @default.
- W2074505983 hasConcept C124815738 @default.
- W2074505983 hasConcept C147789679 @default.
- W2074505983 hasConcept C153609361 @default.
- W2074505983 hasConcept C171250308 @default.
- W2074505983 hasConcept C178790620 @default.
- W2074505983 hasConcept C185592680 @default.
- W2074505983 hasConcept C192562407 @default.
- W2074505983 hasConcept C2778375661 @default.
- W2074505983 hasConcept C2779133857 @default.
- W2074505983 hasConcept C2781123555 @default.
- W2074505983 hasConcept C36591836 @default.
- W2074505983 hasConcept C39271989 @default.
- W2074505983 hasConcept C43617362 @default.
- W2074505983 hasConcept C517785266 @default.
- W2074505983 hasConcept C526903357 @default.
- W2074505983 hasConcept C537181965 @default.
- W2074505983 hasConcept C55493867 @default.
- W2074505983 hasConcept C76272257 @default.
- W2074505983 hasConceptScore W2074505983C113196181 @default.
- W2074505983 hasConceptScore W2074505983C124815738 @default.
- W2074505983 hasConceptScore W2074505983C147789679 @default.
- W2074505983 hasConceptScore W2074505983C153609361 @default.
- W2074505983 hasConceptScore W2074505983C171250308 @default.
- W2074505983 hasConceptScore W2074505983C178790620 @default.
- W2074505983 hasConceptScore W2074505983C185592680 @default.
- W2074505983 hasConceptScore W2074505983C192562407 @default.
- W2074505983 hasConceptScore W2074505983C2778375661 @default.
- W2074505983 hasConceptScore W2074505983C2779133857 @default.
- W2074505983 hasConceptScore W2074505983C2781123555 @default.
- W2074505983 hasConceptScore W2074505983C36591836 @default.
- W2074505983 hasConceptScore W2074505983C39271989 @default.
- W2074505983 hasConceptScore W2074505983C43617362 @default.
- W2074505983 hasConceptScore W2074505983C517785266 @default.
- W2074505983 hasConceptScore W2074505983C526903357 @default.
- W2074505983 hasConceptScore W2074505983C537181965 @default.
- W2074505983 hasConceptScore W2074505983C55493867 @default.
- W2074505983 hasConceptScore W2074505983C76272257 @default.
- W2074505983 hasIssue "3" @default.
- W2074505983 hasLocation W20745059831 @default.
- W2074505983 hasLocation W20745059832 @default.
- W2074505983 hasLocation W20745059833 @default.
- W2074505983 hasOpenAccess W2074505983 @default.
- W2074505983 hasPrimaryLocation W20745059831 @default.
- W2074505983 hasRelatedWork W1975518622 @default.
- W2074505983 hasRelatedWork W1984950613 @default.
- W2074505983 hasRelatedWork W2009659059 @default.
- W2074505983 hasRelatedWork W2026616254 @default.
- W2074505983 hasRelatedWork W2074505983 @default.
- W2074505983 hasRelatedWork W2091746893 @default.
- W2074505983 hasRelatedWork W2127280862 @default.
- W2074505983 hasRelatedWork W2166083222 @default.
- W2074505983 hasRelatedWork W2264512282 @default.
- W2074505983 hasRelatedWork W2415730563 @default.
- W2074505983 hasVolume "218" @default.
- W2074505983 isParatext "false" @default.
- W2074505983 isRetracted "false" @default.
- W2074505983 magId "2074505983" @default.
- W2074505983 workType "article" @default.