FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074547900> ?p ?o ?g. }

• W2074547900 endingPage "167" @default.
• W2074547900 startingPage "161" @default.
• W2074547900 abstract "Abstract: Pruritus is an important symptom in atopic dermatitis (AD), but the major pruritogen have not been identified. NC/Nga mice, spontaneously develop an eczematous AD‐like skin lesion when kept under conventional conditions, but not under specific pathogen‐free (SPF) conditions, have been thought to be an animal model for AD. In this study, to determine whether newly identified cytokine, IL‐31, may be involved in pruritus of AD, we examined the IL‐31 expression in spontaneous dermatitis model which showed itch‐associated long‐lasting (over 1.5 s duration) scratching behavior and compared with that of hapten‐induced contact dermatitis model without itch‐associated long‐lasting scratching behavior, using NC/Nga mice. In NC/Nga mice cohabited with NC/Nga mice which developed severe dermatitis for 2 weeks (conventional NC/Nga mice), the numbers of long‐lasting scratching counts were significantly increased. Yet in 2,4,6‐trinitrochlorobenzene (TNCB)‐sensitized and challenged mice (TNCB‐applied NC/Nga mice), no significant increase in long‐lasting scratching counts was observed. In conventional NC/Nga mice with long‐lasting scratching behavior, expression of IL‐31 mRNA was increased, while in TNCB‐applied NC/Nga mice without long‐lasting scratching behavior, the expression of IL‐31 mRNA were unchanged. There was a good correlation between the scratching counts and expression of IL‐31 mRNA in conventional NC/Nga mice, but not so in TNCB‐applied NC/Nga mice. These results suggest that IL‐31 causes the itch‐associated scratching behavior in conventional NC/Nga mice, an experimental animal model for AD." @default.
• W2074547900 created "2016-06-24" @default.
• W2074547900 creator A5002265537 @default.
• W2074547900 creator A5003900367 @default.
• W2074547900 creator A5025103209 @default.
• W2074547900 creator A5030793371 @default.
• W2074547900 creator A5033287685 @default.
• W2074547900 creator A5052700281 @default.
• W2074547900 creator A5079970882 @default.
• W2074547900 date "2006-02-15" @default.
• W2074547900 modified "2023-10-12" @default.
• W2074547900 title "Involvement of IL-31 on scratching behavior in NC/Nga mice with atopic-like dermatitis" @default.
• W2074547900 cites W1966146079 @default.
• W2074547900 cites W1966170746 @default.
• W2074547900 cites W1970140945 @default.
• W2074547900 cites W1978967991 @default.
• W2074547900 cites W1985146550 @default.
• W2074547900 cites W1991195369 @default.
• W2074547900 cites W1999174354 @default.
• W2074547900 cites W2008795839 @default.
• W2074547900 cites W2020903065 @default.
• W2074547900 cites W2025616494 @default.
• W2074547900 cites W2032062642 @default.
• W2074547900 cites W2035183016 @default.
• W2074547900 cites W2045767946 @default.
• W2074547900 cites W2053113974 @default.
• W2074547900 cites W2054450203 @default.
• W2074547900 cites W2055718153 @default.
• W2074547900 cites W2056271813 @default.
• W2074547900 cites W2065844939 @default.
• W2074547900 cites W2074105245 @default.
• W2074547900 cites W2087358128 @default.
• W2074547900 cites W2091729488 @default.
• W2074547900 cites W2093276424 @default.
• W2074547900 cites W2121696462 @default.
• W2074547900 cites W2129285340 @default.
• W2074547900 cites W2137722996 @default.
• W2074547900 cites W2154376533 @default.
• W2074547900 cites W4232510995 @default.
• W2074547900 cites W4236909385 @default.
• W2074547900 cites W67635794 @default.
• W2074547900 doi "https://doi.org/10.1111/j.1600-0625.2006.00405.x" @default.
• W2074547900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16480423" @default.
• W2074547900 hasPublicationYear "2006" @default.
• W2074547900 type Work @default.
• W2074547900 sameAs 2074547900 @default.
• W2074547900 citedByCount "132" @default.
• W2074547900 countsByYear W20745479002012 @default.
• W2074547900 countsByYear W20745479002013 @default.
• W2074547900 countsByYear W20745479002014 @default.
• W2074547900 countsByYear W20745479002015 @default.
• W2074547900 countsByYear W20745479002016 @default.
• W2074547900 countsByYear W20745479002017 @default.
• W2074547900 countsByYear W20745479002018 @default.
• W2074547900 countsByYear W20745479002019 @default.
• W2074547900 countsByYear W20745479002020 @default.
• W2074547900 countsByYear W20745479002021 @default.
• W2074547900 countsByYear W20745479002022 @default.
• W2074547900 countsByYear W20745479002023 @default.
• W2074547900 crossrefType "journal-article" @default.
• W2074547900 hasAuthorship W2074547900A5002265537 @default.
• W2074547900 hasAuthorship W2074547900A5003900367 @default.
• W2074547900 hasAuthorship W2074547900A5025103209 @default.
• W2074547900 hasAuthorship W2074547900A5030793371 @default.
• W2074547900 hasAuthorship W2074547900A5033287685 @default.
• W2074547900 hasAuthorship W2074547900A5052700281 @default.
• W2074547900 hasAuthorship W2074547900A5079970882 @default.
• W2074547900 hasConcept C121332964 @default.
• W2074547900 hasConcept C203014093 @default.
• W2074547900 hasConcept C24890656 @default.
• W2074547900 hasConcept C2522874641 @default.
• W2074547900 hasConcept C2778329239 @default.
• W2074547900 hasConcept C2778690821 @default.
• W2074547900 hasConcept C2779600528 @default.
• W2074547900 hasConcept C2780196728 @default.
• W2074547900 hasConcept C71924100 @default.
• W2074547900 hasConceptScore W2074547900C121332964 @default.
• W2074547900 hasConceptScore W2074547900C203014093 @default.
• W2074547900 hasConceptScore W2074547900C24890656 @default.
• W2074547900 hasConceptScore W2074547900C2522874641 @default.
• W2074547900 hasConceptScore W2074547900C2778329239 @default.
• W2074547900 hasConceptScore W2074547900C2778690821 @default.
• W2074547900 hasConceptScore W2074547900C2779600528 @default.
• W2074547900 hasConceptScore W2074547900C2780196728 @default.
• W2074547900 hasConceptScore W2074547900C71924100 @default.
• W2074547900 hasIssue "3" @default.
• W2074547900 hasLocation W20745479001 @default.
• W2074547900 hasLocation W20745479002 @default.
• W2074547900 hasOpenAccess W2074547900 @default.
• W2074547900 hasPrimaryLocation W20745479001 @default.
• W2074547900 hasRelatedWork W13033540 @default.
• W2074547900 hasRelatedWork W1980331248 @default.
• W2074547900 hasRelatedWork W2002010381 @default.
• W2074547900 hasRelatedWork W2007842360 @default.
• W2074547900 hasRelatedWork W2011602713 @default.
• W2074547900 hasRelatedWork W2025616494 @default.
• W2074547900 hasRelatedWork W2109299749 @default.
• W2074547900 hasRelatedWork W2118193002 @default.

• next