FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074559523> ?p ?o ?g. }

• W2074559523 endingPage "1203" @default.
• W2074559523 startingPage "1196" @default.
• W2074559523 abstract "Excess risk of cardiovascular disease occurs in effectively treated individuals with human immunodeficiency virus (HIV) infection. Although elevated plasma D-dimer levels are associated with increased morbidity and mortality, the impact of HIV infection on coagulation in vivo has not been well studied.We measured D-dimers, antithrombin, endogenous thrombin potential (ETP; a functional measure of thrombin generation in vitro), thrombin/antithrombin complexes (TAT; a measure of thrombin generation in vivo), tissue factor, prothrombin fragment 1 + 2 (F1+2), and normalized APC sensitivity ratio (nAPCsr) in 199 HIV-positive men who were receiving antiretroviral therapy and had an undetectable HIV RNA level, in 79 HIV-positive untreated men, and in 39 uninfected controls.Median antithrombin levels were higher while the ETP was lower among HIV-infected adults (treated and untreated), compared with controls. There were few differences between coagulation markers in the 2 HIV groups. Compared with controls, the nAPCsr was lower in treated men and the TAT level was lower in untreated individuals. We observed little difference among measured levels of D-dimer, tissue factor, or F1+2 between HIV-infected individuals and controls. Antiretroviral therapy exposure was associated with a lower antithrombin level, a lower nAPCsr, and a lower ETP, while history of opportunistic infection was associated with a higher nAPCsr.HIV infection is associated with decreased thrombin generation, as measured by the ETP, and an increased antithrombin level. These data suggest that HIV infection may not be associated with increased propensity toward clotting, as has been suggested on the basis of isolated measures of D-dimer levels." @default.
• W2074559523 created "2016-06-24" @default.
• W2074559523 creator A5003081987 @default.
• W2074559523 creator A5009636499 @default.
• W2074559523 creator A5020428787 @default.
• W2074559523 creator A5028846143 @default.
• W2074559523 creator A5044517988 @default.
• W2074559523 creator A5048434963 @default.
• W2074559523 creator A5050682541 @default.
• W2074559523 creator A5063704053 @default.
• W2074559523 creator A5073573353 @default.
• W2074559523 creator A5076450702 @default.
• W2074559523 date "2012-04-15" @default.
• W2074559523 modified "2023-09-23" @default.
• W2074559523 title "HIV Infection Is Associated With Decreased Thrombin Generation" @default.
• W2074559523 cites W1970393874 @default.
• W2074559523 cites W1991557600 @default.
• W2074559523 cites W1993407442 @default.
• W2074559523 cites W2015440060 @default.
• W2074559523 cites W2019523317 @default.
• W2074559523 cites W2024773717 @default.
• W2074559523 cites W2043042097 @default.
• W2074559523 cites W2046166857 @default.
• W2074559523 cites W2057674099 @default.
• W2074559523 cites W2071039800 @default.
• W2074559523 cites W2076916940 @default.
• W2074559523 cites W2080536411 @default.
• W2074559523 cites W2082564302 @default.
• W2074559523 cites W2093931830 @default.
• W2074559523 cites W2118247493 @default.
• W2074559523 cites W2121850733 @default.
• W2074559523 cites W2127517680 @default.
• W2074559523 cites W2130680989 @default.
• W2074559523 cites W2138694347 @default.
• W2074559523 cites W2140573695 @default.
• W2074559523 cites W2153136696 @default.
• W2074559523 cites W2167709851 @default.
• W2074559523 cites W2331041808 @default.
• W2074559523 cites W46341902 @default.
• W2074559523 doi "https://doi.org/10.1093/cid/cis014" @default.
• W2074559523 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3309887" @default.
• W2074559523 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22438347" @default.
• W2074559523 hasPublicationYear "2012" @default.
• W2074559523 type Work @default.
• W2074559523 sameAs 2074559523 @default.
• W2074559523 citedByCount "22" @default.
• W2074559523 countsByYear W20745595232012 @default.
• W2074559523 countsByYear W20745595232013 @default.
• W2074559523 countsByYear W20745595232014 @default.
• W2074559523 countsByYear W20745595232015 @default.
• W2074559523 countsByYear W20745595232016 @default.
• W2074559523 countsByYear W20745595232017 @default.
• W2074559523 countsByYear W20745595232018 @default.
• W2074559523 countsByYear W20745595232020 @default.
• W2074559523 countsByYear W20745595232021 @default.
• W2074559523 crossrefType "journal-article" @default.
• W2074559523 hasAuthorship W2074559523A5003081987 @default.
• W2074559523 hasAuthorship W2074559523A5009636499 @default.
• W2074559523 hasAuthorship W2074559523A5020428787 @default.
• W2074559523 hasAuthorship W2074559523A5028846143 @default.
• W2074559523 hasAuthorship W2074559523A5044517988 @default.
• W2074559523 hasAuthorship W2074559523A5048434963 @default.
• W2074559523 hasAuthorship W2074559523A5050682541 @default.
• W2074559523 hasAuthorship W2074559523A5063704053 @default.
• W2074559523 hasAuthorship W2074559523A5073573353 @default.
• W2074559523 hasAuthorship W2074559523A5076450702 @default.
• W2074559523 hasBestOaLocation W20745595231 @default.
• W2074559523 hasConcept C126322002 @default.
• W2074559523 hasConcept C142462285 @default.
• W2074559523 hasConcept C150903083 @default.
• W2074559523 hasConcept C186738567 @default.
• W2074559523 hasConcept C203014093 @default.
• W2074559523 hasConcept C207001950 @default.
• W2074559523 hasConcept C2777292125 @default.
• W2074559523 hasConcept C2777557582 @default.
• W2074559523 hasConcept C2778382381 @default.
• W2074559523 hasConcept C2779026020 @default.
• W2074559523 hasConcept C2779519742 @default.
• W2074559523 hasConcept C3013748606 @default.
• W2074559523 hasConcept C71924100 @default.
• W2074559523 hasConcept C86803240 @default.
• W2074559523 hasConcept C89560881 @default.
• W2074559523 hasConceptScore W2074559523C126322002 @default.
• W2074559523 hasConceptScore W2074559523C142462285 @default.
• W2074559523 hasConceptScore W2074559523C150903083 @default.
• W2074559523 hasConceptScore W2074559523C186738567 @default.
• W2074559523 hasConceptScore W2074559523C203014093 @default.
• W2074559523 hasConceptScore W2074559523C207001950 @default.
• W2074559523 hasConceptScore W2074559523C2777292125 @default.
• W2074559523 hasConceptScore W2074559523C2777557582 @default.
• W2074559523 hasConceptScore W2074559523C2778382381 @default.
• W2074559523 hasConceptScore W2074559523C2779026020 @default.
• W2074559523 hasConceptScore W2074559523C2779519742 @default.
• W2074559523 hasConceptScore W2074559523C3013748606 @default.
• W2074559523 hasConceptScore W2074559523C71924100 @default.
• W2074559523 hasConceptScore W2074559523C86803240 @default.
• W2074559523 hasConceptScore W2074559523C89560881 @default.
• W2074559523 hasIssue "8" @default.

• next