FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074582307> ?p ?o ?g. }

• W2074582307 endingPage "227" @default.
• W2074582307 startingPage "209" @default.
• W2074582307 abstract "This study is a light microscopic investigation of the normal pattern of morphogenesis in the chick tangential nucleus. Rapid Golgi and reduced silver methods have been used to reconstruct the sequences of morphological changes in the developing neurons and colossal-fiber endings of the vestibular nerve in a staged series of chick embryos. The distinctive morphology of the principal and elongate cells and of the colossal fibers and their spoon endings permits the rigorous identification of these structures from very early stages of development. Three stages are discussed: the cell migration stage from 4½ to 6½ days (Hamburger-Hamilton, Stages 25–29), the young neuron stage from 6½ to 8 days (Stages 30–34), and the stage of spoon formation from 8½ to 13 days (Stages 35–39). In the cell migration stage, although the vestibular nerve fibers have already grown into the medulla, no cell bodies appear within the presumptive tangential nucleus in embryos younger than 6 days (Stage 29), nor are the prospective colossal fibers distinguishable by their axonal diameters. The presumptive tangential nucleus contains the external processes of primitive epithelial cells which extend from the matrix zone to the external limiting layer; these cells in 6–7 day (Stage 30) embryos give rise to the migratory neuroblasts which appear in the mantle zone medial to, and also within, the primordial tangential nucleus. The perikarya of the migratory neuroblasts move through the primitive external processes to the presumptive tangential nucleus, while their primitive internal processes withdraw from the matrix zone and reduce to shorter trailing processes. In the young neuron stage the axon of the principal cell emerges from the primitive internal process at a point far medial to the perikaryon; this outgrowth can occur even before the translocation of the nucleus is completed. The colossal fibers are first distinguishable by their greatly enlarged diameters. During the rest of this stage, the post-migratory neuroblasts lose their primitive processes and begin to form dendrites that continue to develop during the next stage. At the beginning of the stage of spoon formation, each colossal fiber forms a characteristic swelling en passant within the tangential nucleus. By 10 days (Stage 36) a sheet-like outgrowth appears just medial to the swelling, which soon disappears as this outgrowth continues to expand over the principal cell soma to form a young spoon ending. It is concluded that the principal cells undergo a specific, time-locked sequence of structural changes in their development, which proceeds in advance of an equally strict sequence of events in the differentiation of the spoon endings that contact these cells. These findings indicate that the ingrowth of the colossal fibers does not initiate cell migration and differentiation in the tangential nucleus, although the fibers and spoon endings could influence subsequent cell development and maintenance. Perhaps the formation of spoon endings depends on migration and differentiation of the principal cells." @default.
• W2074582307 created "2016-06-24" @default.
• W2074582307 creator A5020596818 @default.
• W2074582307 creator A5029002412 @default.
• W2074582307 date "1977-04-01" @default.
• W2074582307 modified "2023-09-27" @default.
• W2074582307 title "A morphological study of neurogenesis in the nucleus vestibularis tangentialis of the chick embryo" @default.
• W2074582307 cites W1991104518 @default.
• W2074582307 cites W1993011138 @default.
• W2074582307 cites W1999349500 @default.
• W2074582307 cites W2000996643 @default.
• W2074582307 cites W2007820716 @default.
• W2074582307 cites W2015428327 @default.
• W2074582307 cites W2031477769 @default.
• W2074582307 cites W2047089209 @default.
• W2074582307 cites W2067983656 @default.
• W2074582307 cites W2070088176 @default.
• W2074582307 cites W2070603983 @default.
• W2074582307 cites W2078885383 @default.
• W2074582307 cites W2082957370 @default.
• W2074582307 cites W2084686265 @default.
• W2074582307 cites W2140034535 @default.
• W2074582307 cites W2165254456 @default.
• W2074582307 doi "https://doi.org/10.1016/0306-4522(77)90090-2" @default.
• W2074582307 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/904775" @default.
• W2074582307 hasPublicationYear "1977" @default.
• W2074582307 type Work @default.
• W2074582307 sameAs 2074582307 @default.
• W2074582307 citedByCount "45" @default.
• W2074582307 countsByYear W20745823072014 @default.
• W2074582307 countsByYear W20745823072018 @default.
• W2074582307 countsByYear W20745823072019 @default.
• W2074582307 crossrefType "journal-article" @default.
• W2074582307 hasAuthorship W2074582307A5020596818 @default.
• W2074582307 hasAuthorship W2074582307A5029002412 @default.
• W2074582307 hasConcept C104317684 @default.
• W2074582307 hasConcept C105702510 @default.
• W2074582307 hasConcept C169760540 @default.
• W2074582307 hasConcept C17291353 @default.
• W2074582307 hasConcept C196843134 @default.
• W2074582307 hasConcept C2777831001 @default.
• W2074582307 hasConcept C2780723820 @default.
• W2074582307 hasConcept C39961270 @default.
• W2074582307 hasConcept C40692019 @default.
• W2074582307 hasConcept C4746552 @default.
• W2074582307 hasConcept C529278444 @default.
• W2074582307 hasConcept C55493867 @default.
• W2074582307 hasConcept C86803240 @default.
• W2074582307 hasConcept C95444343 @default.
• W2074582307 hasConceptScore W2074582307C104317684 @default.
• W2074582307 hasConceptScore W2074582307C105702510 @default.
• W2074582307 hasConceptScore W2074582307C169760540 @default.
• W2074582307 hasConceptScore W2074582307C17291353 @default.
• W2074582307 hasConceptScore W2074582307C196843134 @default.
• W2074582307 hasConceptScore W2074582307C2777831001 @default.
• W2074582307 hasConceptScore W2074582307C2780723820 @default.
• W2074582307 hasConceptScore W2074582307C39961270 @default.
• W2074582307 hasConceptScore W2074582307C40692019 @default.
• W2074582307 hasConceptScore W2074582307C4746552 @default.
• W2074582307 hasConceptScore W2074582307C529278444 @default.
• W2074582307 hasConceptScore W2074582307C55493867 @default.
• W2074582307 hasConceptScore W2074582307C86803240 @default.
• W2074582307 hasConceptScore W2074582307C95444343 @default.
• W2074582307 hasIssue "2" @default.
• W2074582307 hasLocation W20745823071 @default.
• W2074582307 hasLocation W20745823072 @default.
• W2074582307 hasOpenAccess W2074582307 @default.
• W2074582307 hasPrimaryLocation W20745823071 @default.
• W2074582307 hasRelatedWork W1533522542 @default.
• W2074582307 hasRelatedWork W1569775194 @default.
• W2074582307 hasRelatedWork W2059817147 @default.
• W2074582307 hasRelatedWork W2067524998 @default.
• W2074582307 hasRelatedWork W2097686811 @default.
• W2074582307 hasRelatedWork W2285768578 @default.
• W2074582307 hasRelatedWork W2291723575 @default.
• W2074582307 hasRelatedWork W2359055362 @default.
• W2074582307 hasRelatedWork W2411204641 @default.
• W2074582307 hasRelatedWork W2621162928 @default.
• W2074582307 hasVolume "2" @default.
• W2074582307 isParatext "false" @default.
• W2074582307 isRetracted "false" @default.
• W2074582307 magId "2074582307" @default.
• W2074582307 workType "article" @default.