Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074610400> ?p ?o ?g. }
- W2074610400 endingPage "184" @default.
- W2074610400 startingPage "177" @default.
- W2074610400 abstract "Evidence that inflammatory and immune mechanisms may have a critical role in the development of vasospasm after subarachnoid hemorrhage is accumulating. We examined, therefore, whether induction of immunological tolerance to the adhesion molecule that is uniquely expressed on activated endothelium, E-selectin, could inhibit the vasospasm provoked by subarachnoid blood in a rat subarachnoid hemorrhage model. We found that intranasal instillation of E-selectin every other day for 10 days on a mucosal tolerization schedule suppressed delayed type hypersensitivity to E-selectin confirming tolerance to that molecule and markedly suppressed basilar artery spasm after subarachnoid hemorrhage. The results of this proof-of-concept study suggest that agents that can mimic the local effects of the mediators of mucosal tolerance could have therapeutic potential for the management of post-subarachnoid hemorrhage vasospasm." @default.
- W2074610400 created "2016-06-24" @default.
- W2074610400 creator A5003602593 @default.
- W2074610400 creator A5026259953 @default.
- W2074610400 creator A5026822647 @default.
- W2074610400 creator A5036008306 @default.
- W2074610400 creator A5044169459 @default.
- W2074610400 creator A5050229489 @default.
- W2074610400 date "2007-02-01" @default.
- W2074610400 modified "2023-09-27" @default.
- W2074610400 title "Intranasal administration of E-selectin to induce immunological tolerization can suppress subarachnoid hemorrhage-induced vasospasm implicating immune and inflammatory mechanisms in its genesis" @default.
- W2074610400 cites W1526621387 @default.
- W2074610400 cites W1607622122 @default.
- W2074610400 cites W1768438545 @default.
- W2074610400 cites W1853022482 @default.
- W2074610400 cites W1981895433 @default.
- W2074610400 cites W1988317772 @default.
- W2074610400 cites W1999457367 @default.
- W2074610400 cites W2001997798 @default.
- W2074610400 cites W2023515067 @default.
- W2074610400 cites W2025445086 @default.
- W2074610400 cites W2030843837 @default.
- W2074610400 cites W2032996332 @default.
- W2074610400 cites W2035114352 @default.
- W2074610400 cites W2040437315 @default.
- W2074610400 cites W2043851379 @default.
- W2074610400 cites W2068865249 @default.
- W2074610400 cites W2088143012 @default.
- W2074610400 cites W2094555298 @default.
- W2074610400 cites W2127720515 @default.
- W2074610400 cites W2129132447 @default.
- W2074610400 cites W2147491616 @default.
- W2074610400 cites W2149292008 @default.
- W2074610400 cites W2149805219 @default.
- W2074610400 cites W2151848546 @default.
- W2074610400 cites W2155789891 @default.
- W2074610400 cites W2334232511 @default.
- W2074610400 cites W288942681 @default.
- W2074610400 cites W3148831699 @default.
- W2074610400 cites W4210962255 @default.
- W2074610400 cites W4211164442 @default.
- W2074610400 doi "https://doi.org/10.1016/j.brainres.2006.09.116" @default.
- W2074610400 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1852471" @default.
- W2074610400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17188657" @default.
- W2074610400 hasPublicationYear "2007" @default.
- W2074610400 type Work @default.
- W2074610400 sameAs 2074610400 @default.
- W2074610400 citedByCount "11" @default.
- W2074610400 countsByYear W20746104002014 @default.
- W2074610400 countsByYear W20746104002017 @default.
- W2074610400 countsByYear W20746104002021 @default.
- W2074610400 crossrefType "journal-article" @default.
- W2074610400 hasAuthorship W2074610400A5003602593 @default.
- W2074610400 hasAuthorship W2074610400A5026259953 @default.
- W2074610400 hasAuthorship W2074610400A5026822647 @default.
- W2074610400 hasAuthorship W2074610400A5036008306 @default.
- W2074610400 hasAuthorship W2074610400A5044169459 @default.
- W2074610400 hasAuthorship W2074610400A5050229489 @default.
- W2074610400 hasBestOaLocation W20746104002 @default.
- W2074610400 hasConcept C126322002 @default.
- W2074610400 hasConcept C16224149 @default.
- W2074610400 hasConcept C203014093 @default.
- W2074610400 hasConcept C2776820941 @default.
- W2074610400 hasConcept C2776914184 @default.
- W2074610400 hasConcept C2777736543 @default.
- W2074610400 hasConcept C2778506911 @default.
- W2074610400 hasConcept C2781012200 @default.
- W2074610400 hasConcept C42219234 @default.
- W2074610400 hasConcept C71924100 @default.
- W2074610400 hasConcept C85663871 @default.
- W2074610400 hasConcept C8891405 @default.
- W2074610400 hasConcept C98274493 @default.
- W2074610400 hasConceptScore W2074610400C126322002 @default.
- W2074610400 hasConceptScore W2074610400C16224149 @default.
- W2074610400 hasConceptScore W2074610400C203014093 @default.
- W2074610400 hasConceptScore W2074610400C2776820941 @default.
- W2074610400 hasConceptScore W2074610400C2776914184 @default.
- W2074610400 hasConceptScore W2074610400C2777736543 @default.
- W2074610400 hasConceptScore W2074610400C2778506911 @default.
- W2074610400 hasConceptScore W2074610400C2781012200 @default.
- W2074610400 hasConceptScore W2074610400C42219234 @default.
- W2074610400 hasConceptScore W2074610400C71924100 @default.
- W2074610400 hasConceptScore W2074610400C85663871 @default.
- W2074610400 hasConceptScore W2074610400C8891405 @default.
- W2074610400 hasConceptScore W2074610400C98274493 @default.
- W2074610400 hasLocation W20746104001 @default.
- W2074610400 hasLocation W20746104002 @default.
- W2074610400 hasLocation W20746104003 @default.
- W2074610400 hasLocation W20746104004 @default.
- W2074610400 hasOpenAccess W2074610400 @default.
- W2074610400 hasPrimaryLocation W20746104001 @default.
- W2074610400 hasRelatedWork W1988846834 @default.
- W2074610400 hasRelatedWork W1997925169 @default.
- W2074610400 hasRelatedWork W2018028464 @default.
- W2074610400 hasRelatedWork W2047084554 @default.
- W2074610400 hasRelatedWork W2133118607 @default.
- W2074610400 hasRelatedWork W2139875855 @default.
- W2074610400 hasRelatedWork W2364102773 @default.