FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074644920> ?p ?o ?g. }

• W2074644920 abstract "Molecular events linking the initial detection of calorie restriction (CR) to changes in gene expression throughout the organism that ultimately retard aging in CR animals are unknown. This study measured changes in gene expression induced by CR and by aging in the hypothalamus, which likely plays a central role in the initial perception of and response to CR. Hypothalamic expression profiling was done in young (4-6 months) ad libitum fed (AL), young CR (2.5-4.5 months of CR), and old (26-28 months) AL male C57BL/6 mice. CR altered the expression of 137 genes and aging altered 1222. Only 8 age-related genes were oppositely regulated by CR. To test whether reduced plasma glucose is a signal in altering hypothalamic gene expression, we examined GLUT4 transgenic mice (C57BL/6 background; 4-6 months), which have reduced plasma glucose similar to that of CR mice. Twenty-seven genes differed between transgenic and non-transgenic mice; nine of these were only altered by CR. The decreased plasma glucose had a limited role in CR mediated hypothalamic gene expression." @default.
• W2074644920 created "2016-06-24" @default.
• W2074644920 creator A5009115236 @default.
• W2074644920 creator A5010981278 @default.
• W2074644920 creator A5013049594 @default.
• W2074644920 creator A5040603860 @default.
• W2074644920 creator A5083247969 @default.
• W2074644920 date "2006-09-01" @default.
• W2074644920 modified "2023-10-16" @default.
• W2074644920 title "Early hypothalamic response to age-dependent gene expression by calorie restriction" @default.
• W2074644920 cites W1488124756 @default.
• W2074644920 cites W1522945668 @default.
• W2074644920 cites W1583148430 @default.
• W2074644920 cites W1608062813 @default.
• W2074644920 cites W1619040158 @default.
• W2074644920 cites W1828412318 @default.
• W2074644920 cites W1861628010 @default.
• W2074644920 cites W1972318216 @default.
• W2074644920 cites W1973446976 @default.
• W2074644920 cites W1983993635 @default.
• W2074644920 cites W1984740130 @default.
• W2074644920 cites W1992933481 @default.
• W2074644920 cites W1993459259 @default.
• W2074644920 cites W1996766050 @default.
• W2074644920 cites W2002715931 @default.
• W2074644920 cites W2004122118 @default.
• W2074644920 cites W2032128993 @default.
• W2074644920 cites W2033095342 @default.
• W2074644920 cites W2038678383 @default.
• W2074644920 cites W2057775179 @default.
• W2074644920 cites W2058737138 @default.
• W2074644920 cites W2061681671 @default.
• W2074644920 cites W2073151196 @default.
• W2074644920 cites W2076918107 @default.
• W2074644920 cites W2083070419 @default.
• W2074644920 cites W2083076197 @default.
• W2074644920 cites W2085143430 @default.
• W2074644920 cites W2090891335 @default.
• W2074644920 cites W2093844611 @default.
• W2074644920 cites W2107012657 @default.
• W2074644920 cites W2109453886 @default.
• W2074644920 cites W2109972881 @default.
• W2074644920 cites W2122743846 @default.
• W2074644920 cites W2150433848 @default.
• W2074644920 cites W2150731405 @default.
• W2074644920 cites W2154977707 @default.
• W2074644920 cites W2158838681 @default.
• W2074644920 cites W2159401204 @default.
• W2074644920 cites W2424085500 @default.
• W2074644920 cites W4249966633 @default.
• W2074644920 cites W4294107304 @default.
• W2074644920 doi "https://doi.org/10.1016/j.neurobiolaging.2005.06.006" @default.
• W2074644920 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16051397" @default.
• W2074644920 hasPublicationYear "2006" @default.
• W2074644920 type Work @default.
• W2074644920 sameAs 2074644920 @default.
• W2074644920 citedByCount "4" @default.
• W2074644920 countsByYear W20746449202015 @default.
• W2074644920 crossrefType "journal-article" @default.
• W2074644920 hasAuthorship W2074644920A5009115236 @default.
• W2074644920 hasAuthorship W2074644920A5010981278 @default.
• W2074644920 hasAuthorship W2074644920A5013049594 @default.
• W2074644920 hasAuthorship W2074644920A5040603860 @default.
• W2074644920 hasAuthorship W2074644920A5083247969 @default.
• W2074644920 hasConcept C102230213 @default.
• W2074644920 hasConcept C104317684 @default.
• W2074644920 hasConcept C126322002 @default.
• W2074644920 hasConcept C134018914 @default.
• W2074644920 hasConcept C141035611 @default.
• W2074644920 hasConcept C150194340 @default.
• W2074644920 hasConcept C161573976 @default.
• W2074644920 hasConcept C18431079 @default.
• W2074644920 hasConcept C2776188179 @default.
• W2074644920 hasConcept C2777003273 @default.
• W2074644920 hasConcept C2778707264 @default.
• W2074644920 hasConcept C2779306644 @default.
• W2074644920 hasConcept C54355233 @default.
• W2074644920 hasConcept C71924100 @default.
• W2074644920 hasConcept C86803240 @default.
• W2074644920 hasConceptScore W2074644920C102230213 @default.
• W2074644920 hasConceptScore W2074644920C104317684 @default.
• W2074644920 hasConceptScore W2074644920C126322002 @default.
• W2074644920 hasConceptScore W2074644920C134018914 @default.
• W2074644920 hasConceptScore W2074644920C141035611 @default.
• W2074644920 hasConceptScore W2074644920C150194340 @default.
• W2074644920 hasConceptScore W2074644920C161573976 @default.
• W2074644920 hasConceptScore W2074644920C18431079 @default.
• W2074644920 hasConceptScore W2074644920C2776188179 @default.
• W2074644920 hasConceptScore W2074644920C2777003273 @default.
• W2074644920 hasConceptScore W2074644920C2778707264 @default.
• W2074644920 hasConceptScore W2074644920C2779306644 @default.
• W2074644920 hasConceptScore W2074644920C54355233 @default.
• W2074644920 hasConceptScore W2074644920C71924100 @default.
• W2074644920 hasConceptScore W2074644920C86803240 @default.
• W2074644920 hasLocation W20746449201 @default.
• W2074644920 hasLocation W20746449202 @default.
• W2074644920 hasOpenAccess W2074644920 @default.
• W2074644920 hasPrimaryLocation W20746449201 @default.
• W2074644920 hasRelatedWork W2018690794 @default.
• W2074644920 hasRelatedWork W2048033775 @default.

• next