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- W2074660916 abstract "Visually driven activity is not required for the establishment of ocular dominance columns, orientation columns, and long-range horizontal connections in visual cortex, although spontaneous activity appears to be necessary. The role of activity may be instructive or simply permissive; evidence for an instructive role requires inquiry into the role of the pattern of activity in shaping cortical circuits. The few experiments that have probed the role of patterned activity include the effects of artificial strabismus, artificial stimulation of the optic nerve, and rewiring visual projections from the retina to the auditory thalamus and cortex. These experiments demonstrate that patterned activity is vital for the maintenance of thalamocortical, local intracortical, and long-range horizontal connections in cortex." @default.
- W2074660916 created "2016-06-24" @default.
- W2074660916 creator A5017312638 @default.
- W2074660916 creator A5024300858 @default.
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- W2074660916 date "1999-10-01" @default.
- W2074660916 modified "2023-10-18" @default.
- W2074660916 title "Rewiring cortex: The role of patterned activity in development and plasticity of neocortical circuits" @default.
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- W2074660916 doi "https://doi.org/10.1002/(sici)1097-4695(199910)41:1<33::aid-neu6>3.0.co;2-1" @default.
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