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• W2074670639 abstract "Background Balloon endoscopy has been accepted as an effective tool for examining the small intestine. Two types of balloon endoscopy, single and double, are commercially available. The difference in performance between these 2 types of balloon endoscopy has not yet been elucidated. Objective To compare the yield of single-balloon endoscopy (SBE) and double-balloon endoscopy (DBE). Design Single-center, randomized, controlled trial. Setting University hospital in Tokyo, Japan. Patients Patients with suspected small-bowel disease. Interventions SBE and DBE. Main Outcome Measurements Outcomes were the total enteroscopy rate, diagnostic yield, complication rate, and clinical outcomes. Analysis was done by intent to treat. Results The study started in April 2008 and was terminated in April 2010 because of an obvious disadvantage for the SBE group. Thirty-eight patients were enrolled in the study; 18 patients were assigned to the SBE group and 20 to the DBE group. The total enteroscopy rate was 0% in the SBE group and 57.1% in the DBE group (P = .002). In terms of complications, the DBE group had 1 patient with Mallory-Weiss syndrome, and the SBE group had 1 patient with hyperamylasemia. There was no difference in the overall diagnosis rate between the SBE and DBE groups (61.1% vs 50.0%, P = .49). There was no difference in therapeutic outcome between the SBE and DBE groups (27.8% vs 35.0%, P = .63). Limitations Relatively small number of study patients. Conclusions Total enteroscopy is more easily performed with DBE than with SBE. Balloon endoscopy has been accepted as an effective tool for examining the small intestine. Two types of balloon endoscopy, single and double, are commercially available. The difference in performance between these 2 types of balloon endoscopy has not yet been elucidated. To compare the yield of single-balloon endoscopy (SBE) and double-balloon endoscopy (DBE). Single-center, randomized, controlled trial. University hospital in Tokyo, Japan. Patients with suspected small-bowel disease. SBE and DBE. Outcomes were the total enteroscopy rate, diagnostic yield, complication rate, and clinical outcomes. Analysis was done by intent to treat. The study started in April 2008 and was terminated in April 2010 because of an obvious disadvantage for the SBE group. Thirty-eight patients were enrolled in the study; 18 patients were assigned to the SBE group and 20 to the DBE group. The total enteroscopy rate was 0% in the SBE group and 57.1% in the DBE group (P = .002). In terms of complications, the DBE group had 1 patient with Mallory-Weiss syndrome, and the SBE group had 1 patient with hyperamylasemia. There was no difference in the overall diagnosis rate between the SBE and DBE groups (61.1% vs 50.0%, P = .49). There was no difference in therapeutic outcome between the SBE and DBE groups (27.8% vs 35.0%, P = .63). Relatively small number of study patients. Total enteroscopy is more easily performed with DBE than with SBE." @default.
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• W2074670639 date "2011-04-01" @default.
• W2074670639 modified "2023-09-30" @default.
• W2074670639 title "Single-balloon versus double-balloon endoscopy for achieving total enteroscopy: a randomized, controlled trial" @default.
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• W2074670639 doi "https://doi.org/10.1016/j.gie.2010.10.047" @default.
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