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• W2074680897 abstract "The incorporation of CaSi2 grains within a polycaprolactone (PCL) framework results in bioactive and biodegradable scaffolds which may be used in bone tissue regeneration. Porous PCL scaffolds were prepared via a combination of salt-leaching and microemulsion methods. To provide markedly different structural environments for the inorganic phase, calcium disilicide powder was either added to a mixed-composition porogen during a given scaffold preparation, or alternatively added to pre-formed scaffolds. Selective fluorescent labeling, scanning electron microscopy (SEM), and energy dispersive X-ray (EDX) analysis were employed to assess scaffold calcification in vitro. The process of CaSi2/PCL scaffold calcification under zero bias, during which calcium phosphate growth is significantly dependent on the structural degradation of CaSi2 grains, has a similar mechanism as the calcium phosphate growth on bioactive glasses/ceramics. The biomineralization of these scaffolds is initiated solely by the silicide phase and can be accelerated by the degradation of the polymer matrix." @default.
• W2074680897 created "2016-06-24" @default.
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• W2074680897 date "2006-09-01" @default.
• W2074680897 modified "2023-10-16" @default.
• W2074680897 title "Biomineralization of calcium disilicide in porous polycaprolactone scaffolds" @default.
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• W2074680897 doi "https://doi.org/10.1016/j.biomaterials.2006.04.031" @default.
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