Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074685771> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2074685771 endingPage "158" @default.
- W2074685771 startingPage "151" @default.
- W2074685771 abstract "The objective of this study was to evaluate the effectiveness and tolerability of citalopram versus citalopram plus paliperidone combination therapy in patients with somatoform disorders (SDs). In this 6-week, randomized, fixed-dose study, 60 patients with SD (ICD-10 F45.0), undifferentiated SD (F45.1), and somatoform autonomic dysfunction (F45.3) were randomly assigned to receive citalopram (20 mg/day) with or without paliperidone (3 mg/day). Four scales were used to evaluate effectiveness and tolerability at baseline and at the end of the second, fourth, and sixth week after treatment: Somatoform Disorders Screening Symptoms-7 (SOMS-7), Hamilton Anxiety Scale (HAMA), 17-item Hamilton Depression Scale (HAMD-17), and Treatment Emergent Symptom Scale (TESS). The rater was blinded to the kind of treatment patients received. (i) In the intention-to-treat population (N=51), the overall response ratio (50% reduction in SMOS-7 scores) was significantly higher in the citalopram–paliperidone group compared with the citalopram group after a 6-week treatment (71.4 vs. 38.10%, χ2=4.71, P=0.03). (ii) The SOMS-7 and somatic subscore of the Hamilton Anxiety Scale (HAMA-SOM) total score of the citalopram plus paliperidone group decreased more significantly than that of the citalopram group, and a significant difference could be observed at the end of 4 weeks of treatment. (iii) There was no significant difference between the two groups in adverse effects, and no serious adverse event was reported in both groups. Our findings indicate that a combination with paliperidone is significantly better than monotherapy with citalopram whether synergistic or add-on for patients with SDs. Our results call for future studies with larger sample sizes and a longer duration to draw more definitive conclusions." @default.
- W2074685771 created "2016-06-24" @default.
- W2074685771 creator A5016201567 @default.
- W2074685771 creator A5027521449 @default.
- W2074685771 creator A5048108779 @default.
- W2074685771 creator A5055299862 @default.
- W2074685771 creator A5059096350 @default.
- W2074685771 creator A5059338233 @default.
- W2074685771 creator A5067069882 @default.
- W2074685771 creator A5068444580 @default.
- W2074685771 creator A5069109169 @default.
- W2074685771 date "2012-05-01" @default.
- W2074685771 modified "2023-09-26" @default.
- W2074685771 title "Combination of citalopram plus paliperidone is better than citalopram alone in the treatment of somatoform disorder" @default.
- W2074685771 doi "https://doi.org/10.1097/yic.0b013e328351c7e8" @default.
- W2074685771 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22367417" @default.
- W2074685771 hasPublicationYear "2012" @default.
- W2074685771 type Work @default.
- W2074685771 sameAs 2074685771 @default.
- W2074685771 citedByCount "13" @default.
- W2074685771 countsByYear W20746857712014 @default.
- W2074685771 countsByYear W20746857712015 @default.
- W2074685771 countsByYear W20746857712016 @default.
- W2074685771 countsByYear W20746857712018 @default.
- W2074685771 countsByYear W20746857712019 @default.
- W2074685771 countsByYear W20746857712022 @default.
- W2074685771 countsByYear W20746857712023 @default.
- W2074685771 crossrefType "journal-article" @default.
- W2074685771 hasAuthorship W2074685771A5016201567 @default.
- W2074685771 hasAuthorship W2074685771A5027521449 @default.
- W2074685771 hasAuthorship W2074685771A5048108779 @default.
- W2074685771 hasAuthorship W2074685771A5055299862 @default.
- W2074685771 hasAuthorship W2074685771A5059096350 @default.
- W2074685771 hasAuthorship W2074685771A5059338233 @default.
- W2074685771 hasAuthorship W2074685771A5067069882 @default.
- W2074685771 hasAuthorship W2074685771A5068444580 @default.
- W2074685771 hasAuthorship W2074685771A5069109169 @default.
- W2074685771 hasConcept C118552586 @default.
- W2074685771 hasConcept C126322002 @default.
- W2074685771 hasConcept C168563851 @default.
- W2074685771 hasConcept C197934379 @default.
- W2074685771 hasConcept C2776412080 @default.
- W2074685771 hasConcept C2777126507 @default.
- W2074685771 hasConcept C2777198177 @default.
- W2074685771 hasConcept C2777490545 @default.
- W2074685771 hasConcept C2778375690 @default.
- W2074685771 hasConcept C2779177272 @default.
- W2074685771 hasConcept C2780494398 @default.
- W2074685771 hasConcept C2908647359 @default.
- W2074685771 hasConcept C558461103 @default.
- W2074685771 hasConcept C71924100 @default.
- W2074685771 hasConcept C99454951 @default.
- W2074685771 hasConceptScore W2074685771C118552586 @default.
- W2074685771 hasConceptScore W2074685771C126322002 @default.
- W2074685771 hasConceptScore W2074685771C168563851 @default.
- W2074685771 hasConceptScore W2074685771C197934379 @default.
- W2074685771 hasConceptScore W2074685771C2776412080 @default.
- W2074685771 hasConceptScore W2074685771C2777126507 @default.
- W2074685771 hasConceptScore W2074685771C2777198177 @default.
- W2074685771 hasConceptScore W2074685771C2777490545 @default.
- W2074685771 hasConceptScore W2074685771C2778375690 @default.
- W2074685771 hasConceptScore W2074685771C2779177272 @default.
- W2074685771 hasConceptScore W2074685771C2780494398 @default.
- W2074685771 hasConceptScore W2074685771C2908647359 @default.
- W2074685771 hasConceptScore W2074685771C558461103 @default.
- W2074685771 hasConceptScore W2074685771C71924100 @default.
- W2074685771 hasConceptScore W2074685771C99454951 @default.
- W2074685771 hasIssue "3" @default.
- W2074685771 hasLocation W20746857711 @default.
- W2074685771 hasLocation W20746857712 @default.
- W2074685771 hasOpenAccess W2074685771 @default.
- W2074685771 hasPrimaryLocation W20746857711 @default.
- W2074685771 hasRelatedWork W2074685771 @default.
- W2074685771 hasRelatedWork W2347246423 @default.
- W2074685771 hasRelatedWork W2349018243 @default.
- W2074685771 hasRelatedWork W2349474898 @default.
- W2074685771 hasRelatedWork W2359376579 @default.
- W2074685771 hasRelatedWork W2361188260 @default.
- W2074685771 hasRelatedWork W2364412922 @default.
- W2074685771 hasRelatedWork W2364778413 @default.
- W2074685771 hasRelatedWork W2377927275 @default.
- W2074685771 hasRelatedWork W2387304927 @default.
- W2074685771 hasVolume "27" @default.
- W2074685771 isParatext "false" @default.
- W2074685771 isRetracted "false" @default.
- W2074685771 magId "2074685771" @default.
- W2074685771 workType "article" @default.