Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074736596> ?p ?o ?g. }
- W2074736596 endingPage "772" @default.
- W2074736596 startingPage "772" @default.
- W2074736596 abstract "The effect of photodynamic therapy (PDT) treatment on the metabolic state of tumor mitochondria is investigated by imaging of tumor redox status. PDT is performed using the photosensitizer pyropheophorbide-2-deoxyglucosamide (Pyro-2DG), which utilizes the glucose import pathway. It is found that Pyro-2DG-induced PDT resulting in a highly oxidized state of tumor mitochondria. This is determined from the redox ratio changes derived from the intrinsic oxidized flavoprotein (Fp) and reduced pyridine nucleotide (PN) [i.e., reduced nicotinamide adenine dinucleotide (NADH)] fluorescence signals observed using a cryoimager. Thus, the redox ratio is a sensitive indicator for providing reliable and informative measurements of PDT-induced tissue damage. In the PDT treated region of the tumor, highly oxidized flavoprotein and diminishing NADH fluorescence is detected, suggesting that flavoprotein and NADH are oxidized by singlet oxygen produced in the photosensitization process." @default.
- W2074736596 created "2016-06-24" @default.
- W2074736596 creator A5005680629 @default.
- W2074736596 creator A5016314993 @default.
- W2074736596 creator A5018172234 @default.
- W2074736596 creator A5048037390 @default.
- W2074736596 creator A5056033605 @default.
- W2074736596 creator A5063900505 @default.
- W2074736596 creator A5075963709 @default.
- W2074736596 creator A5077455510 @default.
- W2074736596 date "2004-01-01" @default.
- W2074736596 modified "2023-09-27" @default.
- W2074736596 title "Redox ratio of mitochondria as an indicator for the response of photodynamic therapy" @default.
- W2074736596 cites W1551334320 @default.
- W2074736596 cites W1892152977 @default.
- W2074736596 cites W1916661321 @default.
- W2074736596 cites W1966840360 @default.
- W2074736596 cites W1990427071 @default.
- W2074736596 cites W1997832835 @default.
- W2074736596 cites W1998424046 @default.
- W2074736596 cites W2015538125 @default.
- W2074736596 cites W2019295139 @default.
- W2074736596 cites W2033345397 @default.
- W2074736596 cites W2039085306 @default.
- W2074736596 cites W2041685462 @default.
- W2074736596 cites W2058452428 @default.
- W2074736596 cites W2062273647 @default.
- W2074736596 cites W2072227605 @default.
- W2074736596 cites W2077628780 @default.
- W2074736596 cites W2085582602 @default.
- W2074736596 cites W2091210609 @default.
- W2074736596 cites W2109344294 @default.
- W2074736596 cites W2125760670 @default.
- W2074736596 cites W2331874435 @default.
- W2074736596 cites W4205290871 @default.
- W2074736596 cites W4211024586 @default.
- W2074736596 cites W4244275708 @default.
- W2074736596 cites W4253258573 @default.
- W2074736596 cites W52704215 @default.
- W2074736596 doi "https://doi.org/10.1117/1.1760759" @default.
- W2074736596 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15250765" @default.
- W2074736596 hasPublicationYear "2004" @default.
- W2074736596 type Work @default.
- W2074736596 sameAs 2074736596 @default.
- W2074736596 citedByCount "47" @default.
- W2074736596 countsByYear W20747365962012 @default.
- W2074736596 countsByYear W20747365962013 @default.
- W2074736596 countsByYear W20747365962014 @default.
- W2074736596 countsByYear W20747365962015 @default.
- W2074736596 countsByYear W20747365962016 @default.
- W2074736596 countsByYear W20747365962017 @default.
- W2074736596 countsByYear W20747365962019 @default.
- W2074736596 countsByYear W20747365962020 @default.
- W2074736596 countsByYear W20747365962022 @default.
- W2074736596 countsByYear W20747365962023 @default.
- W2074736596 crossrefType "journal-article" @default.
- W2074736596 hasAuthorship W2074736596A5005680629 @default.
- W2074736596 hasAuthorship W2074736596A5016314993 @default.
- W2074736596 hasAuthorship W2074736596A5018172234 @default.
- W2074736596 hasAuthorship W2074736596A5048037390 @default.
- W2074736596 hasAuthorship W2074736596A5056033605 @default.
- W2074736596 hasAuthorship W2074736596A5063900505 @default.
- W2074736596 hasAuthorship W2074736596A5075963709 @default.
- W2074736596 hasAuthorship W2074736596A5077455510 @default.
- W2074736596 hasBestOaLocation W20747365961 @default.
- W2074736596 hasConcept C121332964 @default.
- W2074736596 hasConcept C12554922 @default.
- W2074736596 hasConcept C178790620 @default.
- W2074736596 hasConcept C179104552 @default.
- W2074736596 hasConcept C181199279 @default.
- W2074736596 hasConcept C185592680 @default.
- W2074736596 hasConcept C197957613 @default.
- W2074736596 hasConcept C2775859393 @default.
- W2074736596 hasConcept C2776901170 @default.
- W2074736596 hasConcept C2777516457 @default.
- W2074736596 hasConcept C2781323092 @default.
- W2074736596 hasConcept C2781469039 @default.
- W2074736596 hasConcept C28859421 @default.
- W2074736596 hasConcept C48349386 @default.
- W2074736596 hasConcept C540031477 @default.
- W2074736596 hasConcept C55493867 @default.
- W2074736596 hasConcept C55904794 @default.
- W2074736596 hasConcept C62520636 @default.
- W2074736596 hasConcept C71995715 @default.
- W2074736596 hasConcept C75473681 @default.
- W2074736596 hasConcept C75520062 @default.
- W2074736596 hasConcept C86803240 @default.
- W2074736596 hasConcept C91881484 @default.
- W2074736596 hasConceptScore W2074736596C121332964 @default.
- W2074736596 hasConceptScore W2074736596C12554922 @default.
- W2074736596 hasConceptScore W2074736596C178790620 @default.
- W2074736596 hasConceptScore W2074736596C179104552 @default.
- W2074736596 hasConceptScore W2074736596C181199279 @default.
- W2074736596 hasConceptScore W2074736596C185592680 @default.
- W2074736596 hasConceptScore W2074736596C197957613 @default.
- W2074736596 hasConceptScore W2074736596C2775859393 @default.
- W2074736596 hasConceptScore W2074736596C2776901170 @default.
- W2074736596 hasConceptScore W2074736596C2777516457 @default.