Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074764208> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2074764208 endingPage "1823" @default.
- W2074764208 startingPage "1817" @default.
- W2074764208 abstract "The clinical response to treatment is an important indicator of the therapeutic effect of anticancer agents. Its value and interpretation has to be carefully considered within the context that it is used. In daily practice, response assessment is combined with other indicators of the patient's condition to contribute to the decision-making process. In clinical trials, it is widely used to identify and quantify the anti-tumour activity of new agents. In this context, response evaluation is conducted on the basis of strict predefined criteria such as the World Health Organization (WHO) or Response Evaluation Criteria In Solid Tumors (RECIST) criteria. The RECIST criteria have recently been proposed and offer a detailed guidance to perform a response evaluation. Clinical response is also used as an indicator of therapeutic efficacy in combination with other indicators. Its value as a surrogate indicator of a survival benefit remains unclear in most instances and can hardly be established within the framework of a single randomised trial. With the development of new anticancer agents that behave differently to cytotoxics, clinical benefit will have to integrate concepts of disease stabilisation or time to progression. Over the next decade, oncologists will be able to assess the biological response before the clinical response, and a lot of work and energy will have to be dedicated to assess the predictive and, possibly, the prognostic value of the biological response with regard to the clinical response, as well as more definitive measures of clinical benefit." @default.
- W2074764208 created "2016-06-24" @default.
- W2074764208 creator A5058820647 @default.
- W2074764208 date "2002-09-01" @default.
- W2074764208 modified "2023-09-24" @default.
- W2074764208 title "Measuring the clinical response. What does it mean?" @default.
- W2074764208 cites W1812456385 @default.
- W2074764208 cites W1889275385 @default.
- W2074764208 cites W1912693401 @default.
- W2074764208 cites W1960713055 @default.
- W2074764208 cites W1973302691 @default.
- W2074764208 cites W1973367494 @default.
- W2074764208 cites W1995634658 @default.
- W2074764208 cites W1996285570 @default.
- W2074764208 cites W2002363083 @default.
- W2074764208 cites W2007753377 @default.
- W2074764208 cites W2055901820 @default.
- W2074764208 cites W2058681718 @default.
- W2074764208 cites W2062938854 @default.
- W2074764208 cites W2080675410 @default.
- W2074764208 cites W2082928681 @default.
- W2074764208 cites W2107907914 @default.
- W2074764208 cites W2116290933 @default.
- W2074764208 cites W2124589535 @default.
- W2074764208 cites W2146062575 @default.
- W2074764208 cites W2155679349 @default.
- W2074764208 cites W2163644951 @default.
- W2074764208 cites W2167805334 @default.
- W2074764208 cites W2246231529 @default.
- W2074764208 doi "https://doi.org/10.1016/s0959-8049(02)00182-x" @default.
- W2074764208 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12204662" @default.
- W2074764208 hasPublicationYear "2002" @default.
- W2074764208 type Work @default.
- W2074764208 sameAs 2074764208 @default.
- W2074764208 citedByCount "115" @default.
- W2074764208 countsByYear W20747642082012 @default.
- W2074764208 countsByYear W20747642082013 @default.
- W2074764208 countsByYear W20747642082014 @default.
- W2074764208 countsByYear W20747642082015 @default.
- W2074764208 countsByYear W20747642082016 @default.
- W2074764208 countsByYear W20747642082017 @default.
- W2074764208 countsByYear W20747642082018 @default.
- W2074764208 countsByYear W20747642082019 @default.
- W2074764208 countsByYear W20747642082020 @default.
- W2074764208 countsByYear W20747642082021 @default.
- W2074764208 countsByYear W20747642082023 @default.
- W2074764208 crossrefType "journal-article" @default.
- W2074764208 hasAuthorship W2074764208A5058820647 @default.
- W2074764208 hasConcept C126322002 @default.
- W2074764208 hasConcept C141341695 @default.
- W2074764208 hasConcept C151730666 @default.
- W2074764208 hasConcept C177713679 @default.
- W2074764208 hasConcept C1862650 @default.
- W2074764208 hasConcept C19527891 @default.
- W2074764208 hasConcept C2779343474 @default.
- W2074764208 hasConcept C2779974597 @default.
- W2074764208 hasConcept C2779984678 @default.
- W2074764208 hasConcept C31760486 @default.
- W2074764208 hasConcept C535046627 @default.
- W2074764208 hasConcept C71924100 @default.
- W2074764208 hasConcept C86803240 @default.
- W2074764208 hasConceptScore W2074764208C126322002 @default.
- W2074764208 hasConceptScore W2074764208C141341695 @default.
- W2074764208 hasConceptScore W2074764208C151730666 @default.
- W2074764208 hasConceptScore W2074764208C177713679 @default.
- W2074764208 hasConceptScore W2074764208C1862650 @default.
- W2074764208 hasConceptScore W2074764208C19527891 @default.
- W2074764208 hasConceptScore W2074764208C2779343474 @default.
- W2074764208 hasConceptScore W2074764208C2779974597 @default.
- W2074764208 hasConceptScore W2074764208C2779984678 @default.
- W2074764208 hasConceptScore W2074764208C31760486 @default.
- W2074764208 hasConceptScore W2074764208C535046627 @default.
- W2074764208 hasConceptScore W2074764208C71924100 @default.
- W2074764208 hasConceptScore W2074764208C86803240 @default.
- W2074764208 hasIssue "14" @default.
- W2074764208 hasLocation W20747642081 @default.
- W2074764208 hasLocation W20747642082 @default.
- W2074764208 hasOpenAccess W2074764208 @default.
- W2074764208 hasPrimaryLocation W20747642081 @default.
- W2074764208 hasRelatedWork W2028889234 @default.
- W2074764208 hasRelatedWork W2125287139 @default.
- W2074764208 hasRelatedWork W2132716888 @default.
- W2074764208 hasRelatedWork W2136006960 @default.
- W2074764208 hasRelatedWork W2395817523 @default.
- W2074764208 hasRelatedWork W2753756048 @default.
- W2074764208 hasRelatedWork W3163838529 @default.
- W2074764208 hasRelatedWork W3185728978 @default.
- W2074764208 hasRelatedWork W4306651278 @default.
- W2074764208 hasRelatedWork W4308624663 @default.
- W2074764208 hasVolume "38" @default.
- W2074764208 isParatext "false" @default.
- W2074764208 isRetracted "false" @default.
- W2074764208 magId "2074764208" @default.
- W2074764208 workType "article" @default.