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• W2074783963 endingPage "3034" @default.
• W2074783963 startingPage "3019" @default.
• W2074783963 abstract "Chitosan (CHT) is a non-toxic and inexpensive compound obtained by deacetylation of chitin, the main component of the exoskeleton of arthropods as well as of the cell walls of many fungi. In agriculture CHT is used to control numerous diseases on various horticultural commodities but, although different mechanisms have been proposed, the exact mode of action of CHT is still unknown. In sycamore (Acer pseudoplatanus L.) cultured cells, CHT induces a set of defense/stress responses that includes production of H2O2 and nitric oxide (NO). We investigated the possible signaling role of these reactive molecules in some CHT-induced responses by means of inhibitors of production and/or scavengers. The results show that both reactive nitrogen and oxygen species are not only a mere symptom of stress conditions but are involved in the responses induced by CHT in sycamore cells. In particular, NO appears to be involved in a cell death form induced by CHT that shows apoptotic features like DNA fragmentation, increase in caspase-3-like activity and release of cytochrome c from the mitochondrion. On the contrary, reactive oxygen species (ROS) appear involved in a cell death form induced by CHT that does not show these apoptotic features but presents increase in lipid peroxidation." @default.
• W2074783963 created "2016-06-24" @default.
• W2074783963 creator A5057254287 @default.
• W2074783963 creator A5065448069 @default.
• W2074783963 date "2015-01-29" @default.
• W2074783963 modified "2023-09-24" @default.
• W2074783963 title "Reactive Oxygen and Nitrogen Species in Defense/Stress Responses Activated by Chitosan in Sycamore Cultured Cells" @default.
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• W2074783963 doi "https://doi.org/10.3390/ijms16023019" @default.
• W2074783963 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4346878" @default.
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• W2074783963 hasPublicationYear "2015" @default.
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