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• W2074792578 abstract "Abstract The effects of chlordimeform and lindane on levels of 5-hydroxytryptamine, tryptophan, and N -acetyl dopamine were studied in the cerebral ganglia of the american cockroach, Periplaneta americana . The effects of chlordimeform on nerve cord levels of 5-hydroxytryptamine, tryptophan, dopamine, and octopamine, and the effect of lindane on cerebral ganglia levels of dopamine were also investigated in this species. Topical applications of chlordimeform deplete 5-hydroxytryptamine and tryptophan from the cerebral ganglia whereas levels of n -acetyl dopamine are elevated. The effect of chlordimeform on these compounds is dose-dependent. Similar chlordimeform-induced effects are observed in the nerve cord, and octopamine levels are also depleted in this tissue following treatment with chlordimeform. A biphasic response to chlordimeform is observed in the nerve cord for dopamine levels with a 40% decrease evident after 2 hr and a 30% increase apparent after 6 hr. In contrast to chlordimeform, lindane does not affect 5-hydroxytryptamine and tryptophan levels in the cebral ganglion but low doses of this insecticide effect increases in brain levels of dopamine and n -acetyl dopamine." @default.
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• W2074792578 date "1985-10-01" @default.
• W2074792578 modified "2023-09-27" @default.
• W2074792578 title "Effects of chlordimeform and lindane on monoamine levels in the central nervous system of the american cockroach, Periplaneta americana L" @default.
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• W2074792578 doi "https://doi.org/10.1016/0048-3575(85)90131-2" @default.
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