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- W2074803506 abstract "The present study investigated the behavioral training-induced c-Fos expression in the nucleus basalis of Meynert (nbM) in differently aged rats. This study demonstrated that the c-Fos expression in nbM was significantly increased and the peak occurred at 2 h after dark-avoidance training. Although the increase of c-Fos expression was also observed after pseudotraining, the number of Fos-like immunoreactive neurons in pseudotrained rats was significantly less than that in dark-avoidance trained rats at each time-point. This result suggested that c-Fos expression might be involved in learning and memory processes. In addition, all the pseudotraining-, training- and memory arousing-induced c-Fos expression was decreased with increasing age, and the decrease was more notable in trained and memory aroused rats. This suggested that the total number of nbM neurons and/or the sensitivity of nbM neurons to experimental manipulations, especially learning and memory performance, might reduce during aging." @default.
- W2074803506 created "2016-06-24" @default.
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- W2074803506 date "2000-10-01" @default.
- W2074803506 modified "2023-09-23" @default.
- W2074803506 title "Behavioral training-induced c-Fos expression in the rat nucleus basalis of Meynert during aging" @default.
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- W2074803506 doi "https://doi.org/10.1016/s0006-8993(00)02765-7" @default.
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