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- W2074863618 abstract "Intravenous lignocaine at a dose of 1.5–2.0 mg/kg is frequently included in intubation protocols for patients with acute severe head injury. This literature review attempts to provide an evidence base for this. A Medline search and review of all relevant articles post-1966 was undertaken. There is evidence that lignocaine has a beneficial effect on intracranial and intraocular pressures. Neuroprotection is demonstrated in some animal models. There is, however, no evidence that lignocaine improves outcome. This article recommends using lignocaine in pre-intubation for patients where a rise in intraocular pressure is a concern (e.g. penetrating eye injury), but cannot, on evidence alone, justify its inclusion in head injury protocols." @default.
- W2074863618 created "2016-06-24" @default.
- W2074863618 creator A5021416774 @default.
- W2074863618 date "2000-12-01" @default.
- W2074863618 modified "2023-09-24" @default.
- W2074863618 title "Intravenous lignocaine as pretreatment for intubation of patients with acute severe head injury" @default.
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- W2074863618 doi "https://doi.org/10.1046/j.1442-2026.2000.00158.x" @default.
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