Matches in SemOpenAlex for { <https://semopenalex.org/work/W2074865312> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2074865312 endingPage "993" @default.
- W2074865312 startingPage "985" @default.
- W2074865312 abstract "To gather preliminary data concerning the feasibility of using seven salivary mRNAs—IL-8; IL-1β; dual specificity phosphatase 1 (DUSP1); H3 histone family 3A (H3F3A); ornithin decarboxylase antizyme 1 (OAZ1); S100 calcium-binding protein P (S100P); and spermidine/spermine N1-acetyltransferase 1 (SAT1)—for detecting development of oral squamous cell carcinoma (OSCC) in oral lichen planus (OLP) patients and OSCC patients whose disease was in remission. Saliva samples were collected from five study groups (25 subjects/group): newly diagnosed OSCC, OSCC-in-remission, disease-active OLP, disease-inactive OLP, and normal controls. The salivary mRNA levels were determined by a pre-amplification RT-qPCR approach with nested gene-specific primers. Mean fold changes between each pair of study groups were analyzed by the Mann–Whitney U test. Salivary levels of OAZ1, S100P, and DUSP1 mRNAs were significantly higher in newly diagnosed OSCC patients, compared to: (1) normal controls (p = 0.003; p = 0.003; and p < 0.001, respectively); (2) OSCC-in-remission (p < 0.001; p = 0.001; and p < 0.001, respectively); (3) disease-active OLP (p < 0.001; p = 0.016; and p < 0.001, respectively); and (4) disease-inactive OLP (p = 0.043; p < 0.001; and p < 0.001, respectively). No significant differences were found in the levels of salivary IL-8, IL-1β, H3F3A, and SAT1 mRNAs between newly diagnosed OSCC patients and the normal controls (p = 0.093, 0.327, 0.764, and 0.560, respectively). Salivary OAZ1, S100P, and DUSP1 mRNAs are candidate biomarkers for detecting OSCC development in OSCC patients in remission and in OLP patients. The results of this study serve as the basis for a further large-scale study which may lead to a non-invasive screening method for early detection of OSCC." @default.
- W2074865312 created "2016-06-24" @default.
- W2074865312 creator A5009082161 @default.
- W2074865312 creator A5026277963 @default.
- W2074865312 creator A5043517198 @default.
- W2074865312 creator A5074429882 @default.
- W2074865312 creator A5081112320 @default.
- W2074865312 creator A5087543035 @default.
- W2074865312 creator A5088612091 @default.
- W2074865312 date "2013-07-28" @default.
- W2074865312 modified "2023-09-27" @default.
- W2074865312 title "Levels of potential oral cancer salivary mRNA biomarkers in oral cancer patients in remission and oral lichen planus patients" @default.
- W2074865312 cites W1502354494 @default.
- W2074865312 cites W1964074906 @default.
- W2074865312 cites W1967888679 @default.
- W2074865312 cites W1969401869 @default.
- W2074865312 cites W1984864627 @default.
- W2074865312 cites W2002442168 @default.
- W2074865312 cites W2011582536 @default.
- W2074865312 cites W2064200041 @default.
- W2074865312 cites W2066369326 @default.
- W2074865312 cites W2066588815 @default.
- W2074865312 cites W2067016788 @default.
- W2074865312 cites W2070472499 @default.
- W2074865312 cites W2073726927 @default.
- W2074865312 cites W2074412163 @default.
- W2074865312 cites W2083907999 @default.
- W2074865312 cites W2086812919 @default.
- W2074865312 cites W2095197048 @default.
- W2074865312 cites W2108244474 @default.
- W2074865312 cites W2116029572 @default.
- W2074865312 cites W2123575729 @default.
- W2074865312 cites W2124223043 @default.
- W2074865312 cites W2124262378 @default.
- W2074865312 cites W2157492306 @default.
- W2074865312 cites W2168897896 @default.
- W2074865312 cites W2324138891 @default.
- W2074865312 doi "https://doi.org/10.1007/s00784-013-1041-0" @default.
- W2074865312 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3864601" @default.
- W2074865312 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23892499" @default.
- W2074865312 hasPublicationYear "2013" @default.
- W2074865312 type Work @default.
- W2074865312 sameAs 2074865312 @default.
- W2074865312 citedByCount "23" @default.
- W2074865312 countsByYear W20748653122014 @default.
- W2074865312 countsByYear W20748653122015 @default.
- W2074865312 countsByYear W20748653122016 @default.
- W2074865312 countsByYear W20748653122017 @default.
- W2074865312 countsByYear W20748653122018 @default.
- W2074865312 countsByYear W20748653122019 @default.
- W2074865312 countsByYear W20748653122020 @default.
- W2074865312 countsByYear W20748653122022 @default.
- W2074865312 countsByYear W20748653122023 @default.
- W2074865312 crossrefType "journal-article" @default.
- W2074865312 hasAuthorship W2074865312A5009082161 @default.
- W2074865312 hasAuthorship W2074865312A5026277963 @default.
- W2074865312 hasAuthorship W2074865312A5043517198 @default.
- W2074865312 hasAuthorship W2074865312A5074429882 @default.
- W2074865312 hasAuthorship W2074865312A5081112320 @default.
- W2074865312 hasAuthorship W2074865312A5087543035 @default.
- W2074865312 hasAuthorship W2074865312A5088612091 @default.
- W2074865312 hasBestOaLocation W20748653122 @default.
- W2074865312 hasConcept C121608353 @default.
- W2074865312 hasConcept C126322002 @default.
- W2074865312 hasConcept C142724271 @default.
- W2074865312 hasConcept C2776201145 @default.
- W2074865312 hasConcept C504460877 @default.
- W2074865312 hasConcept C71924100 @default.
- W2074865312 hasConcept C90924648 @default.
- W2074865312 hasConceptScore W2074865312C121608353 @default.
- W2074865312 hasConceptScore W2074865312C126322002 @default.
- W2074865312 hasConceptScore W2074865312C142724271 @default.
- W2074865312 hasConceptScore W2074865312C2776201145 @default.
- W2074865312 hasConceptScore W2074865312C504460877 @default.
- W2074865312 hasConceptScore W2074865312C71924100 @default.
- W2074865312 hasConceptScore W2074865312C90924648 @default.
- W2074865312 hasIssue "3" @default.
- W2074865312 hasLocation W20748653121 @default.
- W2074865312 hasLocation W20748653122 @default.
- W2074865312 hasLocation W20748653123 @default.
- W2074865312 hasLocation W20748653124 @default.
- W2074865312 hasOpenAccess W2074865312 @default.
- W2074865312 hasPrimaryLocation W20748653121 @default.
- W2074865312 hasRelatedWork W2053027561 @default.
- W2074865312 hasRelatedWork W2070472499 @default.
- W2074865312 hasRelatedWork W2116029572 @default.
- W2074865312 hasRelatedWork W2160580706 @default.
- W2074865312 hasRelatedWork W2348472223 @default.
- W2074865312 hasRelatedWork W2375175453 @default.
- W2074865312 hasRelatedWork W2392774555 @default.
- W2074865312 hasRelatedWork W2582815190 @default.
- W2074865312 hasRelatedWork W3185581151 @default.
- W2074865312 hasRelatedWork W6875337 @default.
- W2074865312 hasVolume "18" @default.
- W2074865312 isParatext "false" @default.
- W2074865312 isRetracted "false" @default.
- W2074865312 magId "2074865312" @default.
- W2074865312 workType "article" @default.